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Environmental Dimension of Antibiotic Resistance

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Tong Zhang, Keiji Fukuda, Edward Topp, Yong-Guan Zhu, Kornelia Smalla, James M Tiedje, D G Joakim Larsson

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Antibiotic resistance is an increasingly recognized global challenge that is threatening human and animal health, food security, and the global economy. The role of the environment in antimicrobial resistance has been listed by the United Nations Environment Program as an emerging issues of concern. Effective policies and actions to combat antibiotic resistance depend on better understanding this problem. This includes factors driving the development of antibiotic resistance, such as current antibiotic usage practices in different sectors, the global scope and nature of the problem, and the most effective mitigation and stewardship practices.

Editorial

Editorial: The Environmental Dimension of Antibiotic Resistance

Tong Zhang, Keiji Fukuda, Edward Topp, Yong-Guan Zhu, Kornelia Smalla, James M Tiedje, D G Joakim Larsson
FEMS Microbiology Ecology, Volume 96, Issue 8, August 2020, fiaa130

This Thematic Topic on the Environmental Dimension of Antibiotic Resistance was launched after the 5th International Symposium on the Environmental Dimension of Antibiotic Resistance (EDAR5). 

Mini Review

Biofilms: hot spots of horizontal gene transfer (HGT) in aquatic environments, with a focus on a new HGT mechanism

Kimihiro Abe, et al.
FEMS Microbiology Ecology, Volume 96, Issue 5, May 2020, fiaa031

Biofilms and membrane vesicles are the stage of gene transfer.

Mini Review

Antimicrobial resistance three ways: healthcare crisis, major concepts and the relevance of biofilms

Paula Jorge, et al.
FEMS Microbiology Ecology, Volume 95, Issue 8, August 2019, fiz115

This minireview not only elucidates the problematic and the major concepts of antimicrobial resistance, but also further focuses on the problematic of biofilms and their resistance and tolerance mechanisms, as well as highlights current research on anti-biofilm strategies.

A generalised model for generalised transduction: the importance of co-evolution and stochasticity in phage mediated antimicrobial resistance transfer

Sankalp Arya, et al.
FEMS Microbiology Ecology, Volume 96, Issue 7, July 2020, fiaa100

Antimicrobial resistance can be spread by viruses that infect bacteria; here we show how we can use mathematical models to describe and analyze this phenomenon.

Editor's Choice

Online searching platform for the antibiotic resistome in bacterial tree of life and global habitats

An Ni Zhang, et al.
FEMS Microbiology Ecology, Volume 96, Issue 7, July 2020, fiaa107

Online searching platform for antibiotic resistome in bacterial tree of life and global habitats by big data mining into 54 718 bacterial genomes, 15 738 bacterial plasmids, 3000 bacterial integrons and 854 environmental metagenomes.

Whole genome sequencing and antibiotic diffusion assays, provide new insight on drug resistance in the genus Pedobacter

Ingvild Falkum Ullmann, et al.
FEMS Microbiology Ecology, Volume 96, Issue 6, June 2020, fiaa088

Whole genome sequencing of the environmental superbugs™ Pedobacter spp. provides insights on their multi-drug resistance.

Persistence of wastewater antibiotic resistant bacteria and their genes in human fecal material

Nazareno Scaccia, et al.
FEMS Microbiology Ecology, Volume 96, Issue 6, June 2020, fiaa058

Antibiotic resistance genes harbored by wastewater bacterial isolates persisted in healthy infant's stool-based microcosms under different conditions, including the presence of sub-inhibitory concentrations of antibiotics.

Antibiotic resistance patterns of Pseudomonas spp. isolated from faecal wastes in the environment and contaminated surface water

Mathilde Camiade, et al.
FEMS Microbiology Ecology, Volume 96, Issue 2, February 2020, fiaa008

Antibiotic resistance pattern in environmental Pseudomonas is species-dependent and can vary from 2 to 9 resistances.

Antibiotic resistome and microbial community structure during anaerobic co-digestion of food waste, paper and cardboard

Kärt Kanger, et al.
FEMS Microbiology Ecology, Volume 96, Issue 2, February 2020, fiaa006

Antibiotic resistome and microbial community structure were studied in a solid-state leach bed anaerobic digester treating food waste, paper and cardboard.

Diversity of methicillin-resistant staphylococci among wild Lepus granatensis: first detection of mecA-MRSA in hares

Vanessa Silva, et al.
FEMS Microbiology Ecology, Volume 96, Issue 1, February 2020, fiz204

First reported description of the presence of mecA-MRSA among wild hares and diversity of other methicillin-resistant staphylococci in wild hares.

The vertical distribution of tetA and intI1 in a deep lake is rather due to sedimentation than to resuspension

Andrea Di Cesare, et al.
FEMS Microbiology Ecology, Volume 96, Issue 2, February 2020, fiaa002

Sedimentation of antibiotic resistance genes in lake water.

Antibiotic-induced gut metabolome and microbiome alterations increase the susceptibility to Candida albicans colonization in the gastrointestinal tract

Daniel Gutierrez, et al.
FEMS Microbiology Ecology, Volume 96, Issue 1, February 2020, fiz187

Gut metabolites and microbiome regulate the gastrointestinal colonization of C. albicans.

Survey of selected antibiotic resistance genes in agricultural and non-agricultural soils in south-central Idaho

Robert S Dungan, et al.
FEMS Microbiology Ecology, Volume 95, Issue 6, June 2019, fiz071

The occurrence and relative abundance of antibiotic resistance and a class 1 integron-integrase genes was greater in manure-amended cropland soils than in other agricultural and non-agricultural soils.

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