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FEMS Microbiology Letters is pleased to offer a thematic issue edited by Dr. Andrew Millard, on the subject of bacteriophages. Over 100 years after the first documented isolation of bacteriophages, this thematic issue illuminates often overlooked areas of the field as well as emerging issues and new discoveries. Topics in this issue range from fundamental molecular biology of bacteriophage biology to descriptions of phage communities from unique environments as well as applied aspects of phage therapy and the associated legislative framework. 

MiniReviews

Safety and efficacy of phage therapy via the intravenous route
Peter Speck, Anthony Smithyman
DOI: http://dx.doi.org/10.1093/femsle/fnv242 fnv242 First published online: 20 December 2015
Abstract     Full Text (HTML)     Full Text (PDF)     Figures & Data

Host receptors for bacteriophage adsorption 
Juliano Bertozzi Silva, Zachary Storms, Dominic Sauvageau
DOI: http://dx.doi.org/10.1093/femsle/fnw002 fnw002 First published online: 10 January 2016
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The role of temperate bacteriophages in bacterial infection 
Emily V. Davies, Craig Winstanley, Joanne L. Fothergill, Chloe E. James
DOI: http://dx.doi.org/10.1093/femsle/fnw015 fnw015 First published online: 28 January 2016
Abstract     Full Text (HTML)     Full Text (PDF)     Figures & Data

Single-stranded DNA phages: from early molecular biology tools to recent revolutions in environmental microbiology 
Anna J. Székely, Mya Breitbart
DOI: http://dx.doi.org/10.1093/femsle/fnw027 fnw027 First published online: 5 February 2016
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Diversity of phage infection types and associated terminology: the problem with ‘Lytic or lysogenic’ 
Zack Hobbs, Stephen T. Abedon
DOI: http://dx.doi.org/10.1093/femsle/fnw047 fnw047 First published online: 29 February 2016
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Bacteriophages of Soft Rot Enterobacteriaceae—a minireview
Robert Czajkowski
DOI: http://dx.doi.org/10.1093/femsle/fnv230 fnv230 First published online: 30 November 2015
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Computational prospecting the great viral unknown 
Bonnie L. Hurwitz, Jana M. U’Ren, Ken Youens-Clark
DOI: http://dx.doi.org/10.1093/femsle/fnw077 fnw077 First published online: 29 March 2016
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Commentaries

A bacteriophage journey at the European Medicines Agency
Lauren Debarbieux, Jean-Paul Pirnay, Gilbert Verbeken, Daniel De Vos, Maia Merabishvili, Isabelle Huys, Olivier Patey, Dirk Schoonjans, Mario Vaneechoutte, Martin Zizi, Christine Rohde
DOI:http://dx.doi.org/10.1093/femsle/fnv225 fnv225 First published online: 10 December 2015
Abstract     Full Text (HTML)     Full Text (PDF)     Figures & Data

Bacteriophage exploitation of bacterial biofilms: phage preference for less mature targets?
Stephen T. Abedon
DOI: http://dx.doi.org/10.1093/femsle/fnv246 fnv246 First published online: 6 January 2016
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Research Letters

Access to bacteriophage therapy: discouraging experiences from the human cell and tissue legal framework
G. Verbeken, I. Huys, D. De Vos, A. De Coninck, D. Roseeuw, E. Kets, A. Vanderkelen, J. P. Draye, T. Rose, S. Jennes, C. Ceulemans,J. P. Pirnay
DOI: http://dx.doi.org/10.1093/femsle/fnv241 fnv241 First published online: 16 December 2015
Abstract     Full Text (HTML)     Full Text (PDF)     Figures & Data
 

Evidence that bacteriophage λ lysogens may induce in response to the proton motive force uncoupler CCCP
Lynn C. Thomason, Donald L. Court
DOI: http://dx.doi.org/10.1093/femsle/fnv244 fnv244 First published online: 23 December 2015
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Experimental evidence for proteins constituting virion components and particle morphogenesis of bacteriophage ZF40
Natalia Korol, An Van den Bossche, Liudmyla Romaniuk, Jean-Paul Noben, Rob Lavigne, Fedor Tovkach
DOI: http://dx.doi.org/10.1093/femsle/fnw042 fnw042 First published online: 16 February 2016
Abstract     Full Text (HTML)     Full Text (PDF)     Figures & Data

Biogeography of bacteriophages at four hydrothermal vent sites in the Antarctic based on g23 sequence diversity 
Andrew D. Millard, David Pearce, Katrin Zwirglmaier
DOI: http://dx.doi.org/10.1093/femsle/fnw043 fnw043 First published online: 22 February 2016
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Natural mummification of the human gut preserves bacteriophage DNA 
Tasha M. Santiago-Rodriguez, Gino Fornaciari, Stefania Luciani, Scot E. Dowd, Gary A. Toranzos, Isolina Marota, Raul J. Cano
DOI: http://dx.doi.org/10.1093/femsle/fnv219 fnv219 First published online: 11 November 2015
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Characterization of LysPBC4, a novel Bacillus cereus-specific endolysin of bacteriophage PBC4 
Hongjun Na, Minsuk Kong, Sangryeol Ryu
DOI: http://dx.doi.org/10.1093/femsle/fnw092 fnw092 First published online: 11 April 2016
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