Editorial Board
Editor-in-Chief
Charis Eng
Cleveland, OH, USA
Sondra J and Stephen R Hardis Professor and Chair, Genomic Medicine Institute Chair and Director, Center for Personalized Genetic Healthcare
Cleveland Clinic
Professor Charis Eng is Chairwoman of the Genomic Medicine Institute, and Chair of its clinical component Center for Personalized Genetic Healthcare at the Cleveland Clinic, as well as Professor and Vice Chair of the Department of Genetics and Genome Sciences at Case Western Reserve University School of Medicine. She has been honoured by the Cleveland Clinic with the Sondra J and Stephen R Hardis endowed chair of cancer genomic medicine and a Lerner Eminent Scholar. Her expertise lies in heritable cancer genomic medicine, and she uses PTEN hamartoma tumour syndrome as her model. Prof. Eng has published over 500 peer-reviewed original research papers and has received numerous awards and honors including the Doris Duke Distinguished Clinical Scientist Award, AAAS Fellow, ASCI, AAP and National Academy of Medicine. She is also Senior Editor of Cancer Research, and Associate Editor of Nature PJ Genomic Medicine, Genome Medicine, and Gastroenterology, and is immediate past Editor-in-Chief of Endocrine-Related Cancer.
Research Interests: Utilization of a multidisciplinary approach, genomic, microbiomic, metabolomic, etc in clinical, cell and animal models, to dissect out the mechanism of phenotypic dichotomy of cancer versus autism spectrum in those with germline PTEN variants.
https://orcid.org/0000-0002-3693-5145Executive Editors: Genome-Wide Association Studies
Eleftheria Zeggini
Munich, Germany
Director
Institute of Translational Genomics
Helmholtz Munich
Liesel Beckmann Distinguished Professor
School of Medicine
Technical University Munich and Klinikum Rechts der Isar
Eleftheria Zeggini is the founding Director of the Institute of Translational Genomics at Helmholtz Munich and holds the TUM Liesel Beckmann Distinguished Professorship at the School of Medicine of the Technical University Munich and Klinikum Rechts der Isar. Her research focuses on dissecting the role of sequence variation in human health and disease by coupling high-throughput sequencing technologies with the study of diverse populations and strategies linking electronic health records to genomics. Her activities are underpinned by the integration of big multi-omics data, and by the development of computational and statistical approaches for the next generation of translational genomics studies.
Andrew P. Morris
Manchester, UK
Professor of Statistical Genetics
Centre for Genetics and Genomics Versus Arthritis
Centre for Musculoskeletal Research
Division of Musculoskeletal and Dermatological Sciences
The University of Manchester
Andrew Morris is Professor of Statistical Genetics and Head of the Division of Musculoskeletal and Dermatological Sciences, at The University of Manchester, UK. Andrew’s research focusses on the development of methodology for the analysis of genome-wide association studies, including multi-ancestry approaches and integration with multi-omics data resources. He co-leads international collaborative efforts to understand the genetic contribution to complex human traits and diseases, including type 2 diabetes, glycaemic traits, kidney function, and blood pressure. He previously served as President of the International Genetic Epidemiology Society.
Topic Editors
Marisa Bartolomei
Philadelphia, PA, USA
Cell and developmental biology, genomic imprinting, epigenetics
Dr. Marisa Bartolomei is the Perelman Professor of Cell & Developmental Biology and co-Director of the Epigenetics Institute at the University of Pennsylvania Perelman School of Medicine. Dr. Bartolomei is the recipient of the 2017 Genetics Society Medal (UK Genetics Society), 2022 Society for the Study of Reproduction Research Award and is a Member of National Academy of Sciences. Her work focuses on mechanisms underlying imprinted gene expression and DNA methylation reprogramming in the germline as well as the impact of early developmental environmental insults on epigenetic gene regulation using the mouse as a model.
Feixiong Cheng
Cleveland, OH, USA
Systems biology, pharmacogenomics, computational genomics
Dr. Cheng is a computational biologist by training, with expertise in analyzing, visualizing, and mining data from real world (e.g., electronic health records, and health care claims) and experiments that profile the molecular state of human cells and tissues by interactomics, transcriptomics, genomics, proteomics, and metabolomics for personalized drug discovery and precise patient care.
Michaela U. Gack
Port St. Lucie, FL, USA
Immunology and infectious diseases, signal transduction
Dr. Gack is the Arthur and Marylin Levitt Endowed Chair and Scientific Director of the Cleveland Clinic Florida Research and Innovation Center. She did her PhD training in virology at Harvard Medical School as part of a collaborative graduate program between Harvard and the Friedrich Alexander University Erlangen-Nuremberg, Germany. Before joining Cleveland Clinic in 2020, she held faculty positions at Harvard University and The University of Chicago.
Dr. Gack is interested in understanding how the intricate interplay between viruses and the human immune response impacts the outcome of viral infection. Another major interest of Dr. Gack are genetic factors that influence the severity of viral infectious diseases or immune-related disorders. For her academic achievements in the fields of virology and innate immunity, Dr. Gack received several awards including the GE & Science Prize for Young Life Scientists, the Robert Koch Postdoctoral Prize, the Merck Irving S. Sigal Memorial Award of the American Society for Microbiology, and she has also been selected twice on Germany’s list of “Top 40 under 40” scientists. In 2017, she was awarded the Vilcek Prize for Creative Promise in Biomedical Science, and in 2021 she received an NIH Director’s PIONEER Award. She is currently serving as an editor for Human Molecular Genetics and she is also a member of the editorial board of Science Signaling.
Debbie J. Marsh
Sydney, Australia
Epigenomics, chromatin remodeling, systems pathology, broad cancer signaling
Professor Deborah Marsh is the Discipline Leader of Medical Science and Head of the Translational Oncology Group in the School of Life Sciences, Faculty of Science at the University of Technology Sydney, Australia. She is a cancer scientist who applies her cell and molecular biology skills to generating new knowledge in women’s cancers, including specifically ovarian cancer, as well as familial cancer syndromes. She has a particular interest in chromatin remodelling and the impact of this on cancer-related gene expression.
Joanne Ngeow
Singapore
Translational studies; cancer genetics/genomics, functional interrogation (cancer only), cancer microbiome
Dr Joanne Ngeow, BMedSci, MBBS, FRCP, MPH is Senior Consultant, Division of Medical Oncology at the National Cancer Centre Singapore and Associate Professor (Genomic Medicine) at the Lee Kong Chian School of Medicine, Nanyang Technological University Singapore. Dr Ngeow currently heads the Cancer Genetics Service at the National Cancer Centre Singapore with an academic interest in hereditary cancer syndromes and translational clinical cancer genetics. Dr Ngeow is funded by the National Medical Research Council and Ministry of Health Singapore to explore how gene-environmental interactions predisposes to cancer initiation and progression and the implementation of genomics into routine clinical care.
Harry Orr
Minneapolis, MN, USA
Neurodegenerative disorders
Dr. Orr is the James Schindler and Bob Allison Translational Research Chair, Director of the Institute of Translational Neuroscience and Professor in the Department of Laboratory Medicine and Pathology at the University of Minnesota Medical School. He obtained his PhD from Washington University in St Louis and did a postdoctoral fellowship at Harvard before joining the University of Minnesota faculty. Orr’s research focuses on the neurodegenerative disease spinocerebellar ataxia type 1 (SCA1). SCA1, a member of a group of polyglutamine neurodegenerative diseases, is caused by expansion of a CAG trinucleotide repeats encoding a stretch of glutamine residues in the affected protein Ataxin-1.
Eric Shoubridge
Montreal, Canada
Mitochondrial disorders
Dr. Shoubridge is a Professor at McGill University, where he leads the Shoubridge Lab. Dr Shoubrige’s laboratory focuses on the molecular genetics of mitochondrial diseases, in particular, those that affect the function of the respiratory chain. His research areas include rare neurological diseases.
Honorary Editors
Kay Davies
Department of Physiology, Anatomy and Genetics
University of Oxford
South Parks Road
Oxford, OX1 3QX
UK
Dr. Anthony Wynshaw-Boris
James H. Jewell MD '34 Professor of Genetics
Chair, Department of Genetics and Genome Sciences
Case Western Reserve University
School of Medicine
10900 Euclid Avenue, BRB731
Cleveland, Ohio 44106-4955
USA
Huntington F. Willard, Ph.D.
Chief Scientific Officer
Genome Medical, Inc.
South San Francisco, CA
Durham, NC
USA
Editorial Board
Lauri A. Aaltonen
Helsinki, Finland
Chris Amos
Houston, TX, USA
Jordana T. Bell
London, UK
Guy A. Caldwell
Tuscaloosa, AL, USA
David Chan
Pasadena, CA, USA
Rui Chen
Houston, TX, USA
Mark R. Cookson
Bethesda, MD, USA
Beverly L. Davidson
Iowa City, IA, USA
Mel B. Feany
Boston, MA, USA
Fred Gage
La Jolla, CA, USA
Daniel Geschwind
Los Angeles, CA, USA
Joseph Gleeson
San Diego, CA, USA
Jonathan L. Haines
Cleveland, OH, USA
Laura M. Huckins
New York, NY, USA
Atsushi Kamiya
Baltimore, USA
Zoltan Kutalik
Lausanne, Switzerland
Janine LaSalle
Davis, CA, USA
Brendan Lee
Houston, TX, USA
He Lin
Shanghai, China
Stanislas Lyonnet
Paris, France
Heather C. Mefford
Seattle, WA, USA
Hikewaki Nakagawa
Tokyo, Japan
Hank Paulson
Ann Arbor, MI, USA
Michele Ramsay
Gauteng, South Africa
Laura Ranum
Gainesville, FL, USA
Renee A. Reijo Pera
Palo Alto, CA, USA
David Rubinsztein
Cambridge, UK
Serena Sanna
Groningen, The Netherlands
Hiroyuki Sasaki
Fukuoka, Japan
Nicholas J. Schork
USA
Val Sheffield
Iowa City, IA, USA
Chen-Yang Shen
Taipei, Taiwan
Leslie Thompson
Irvine, CA, USA
Xiangling Wang
Cleveland, OH, USA
Zhenghe J Wang
Cleveland, OH, USA
Ya-ping Zhang
Kunming, China
Editorial Office
Kirsty Vance
hmg.editorialoffice@oup.com
