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D. McInerney, S. Schnell, R. E. Baker, P. K. Maini, A mathematical formulation for the cell‐cycle model in somitogenesis: analysis, parameter constraints and numerical solutions, Mathematical Medicine and Biology: A Journal of the IMA, Volume 21, Issue 2, June 2004, Pages 85–113, https://doi.org/10.1093/imammb/21.2.85
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Abstract
In this work we present an analysis, supported by numerical simulations, of the formulation of the cell‐cycle model for somitogenesis proposed in Collier et al.(J. Theor. Biol.207 (2000), 305–316). The analysis indicates that by introducing appropriate parameter constraints on model parameters the cell‐cycle mechanism can indeed give rise to the periodic pattern of somites observed in normal embryos. The analysis also provides a greater understanding of the signalling process controlling somite formation and allows us to understand which parameters influence somite length.