Monoclonal Antibodies: Pragmatic Application of Immunology and Cell Biology

Kelley, Keith W.; Lewin, Harris A.

doi:10.2527/jas1986.631288x

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Monoclonal Antibodies: Pragmatic Application of Immunology and Cell Biology

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Abstract

Monoclonal antibodies represent a natural extension of research efforts directed at understanding the structure and function of antibody molecules. In this paper, essential concepts that led to development of monoclonal antibody technology are outlined, including a short discussion on antibody structure and genetics. An overview of the theory of monoclonal antibody production is presented, as well as a comparison of the properties of monoclonal antibodies and conventional antisera. The paper concludes with a discussion of recent innovations in monoclonal antibody technology and their current and potential applications in animal agriculture.

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Monoclonal Antibodies: Pragmatic Application of Immunology and Cell Biology

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