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Research Article
Diet quality and cardiovascular disease risk among breast cancer survivors in the Pathways Study
Isaac J Ergas and others
Background Women with breast cancer are at higher risk of cardiovascular disease (CVD) compared with women without breast cancer. Whether higher diet quality at breast cancer diagnosis lowers this risk remains unknown. We set out to determine if higher diet quality at breast cancer diagnosis was related to lower risk of CVD and CVD-related death. Methods This analysis included 3415 participants ...
Research Article
Derazantinib alone and with atezolizumab in metastatic urothelial carcinoma with activating FGFR aberrations
Andrea Necchi and others
Background This Phase 1 b/2 study assessed the efficacy, in terms of objective response rate (ORR) of the FGFR1/2/3 kinase inhibitor derazantinib as monotherapy or in combination with atezolizumab in patients with metastatic urothelial cancer (mUC) and FGFR1-3 genetic aberrations ( FGFR1-3 GA ). Methods This multicenter, open-label study comprised 5 substudies. In Substudies 1 and 5, patients ...
Editorial
Increased pain in veterans with cancer—time to re-evaluate opioid prescribing practices?
Vikram Jairam
The United States is in the middle of an opioid epidemic. The number of opioid-related overdose deaths in 2021 was at its highest in any year, claiming more than 80 000 lives ( 1 ). This is primarily due to an increase in synthetic opioids, such as fentanyl, responsible for 70 000 overdose-related deaths. Meanwhile, prescription opioid deaths rose steadily from 2000 and peaked in 2017, now having ...
Editorial
Novel insights on multilevel factors that affect the dynamic course of financial toxicity in cancer patients
Grace L Smith
Grace L. Smith, MD, PhD, MPH (Conceptualization; Investigation; Methodology; Writing—original draft; Writing—review & editing). None. Not related to this manuscript, GLS reports grant funding from Genentech and consulting fees from Astra Zeneca. Financial toxicity is one of the most ubiquitous impacts of disease and treatment in individuals who have had a cancer diagnosis. The financial ...
Brief Report
Salpingectomy for ectopic pregnancy reduces ovarian cancer risk—a nation-wide study
Ju-Chuan Yen and others
Recent studies propose fallopian tubes as the tissue origin for many ovarian epithelial cancers. To further support this paradigm, we assessed whether salpingectomy for treating ectopic pregnancy had a protective effect using the Taiwan Longitudinal National-Health-Research Database. We identified 316,882 women with surgical treatment for ectopic pregnancy and 3,168,820 age- and ...
Brief Report
Association of breast cancer with quantitative mammographic density measures for women receiving contrast-enhanced mammography
Gordon P Watt and others
Women with high mammographic density (MD) have an increased risk of breast cancer. They may be offered contrast-enhanced mammogram (CEM) to improve breast cancer screening performance. Using a cohort of women receiving CEM, we evaluated whether conventional and modified MD measures were associated with breast cancer. Sixty-six cases with newly diagnosed unilateral breast cancer were ...
Research Article
Prediction of cognitive decline in older breast cancer survivors: the thinking and living with cancer study
Arthur Patrick Mcdeed and others
Purpose Cancer survivors commonly report cognitive declines after cancer therapy. Due to the complex etiology of cancer-related cognitive decline (CRCD), predicting who will be at risk of CRCD remains a clinical challenge. We developed a model to predict breast cancer survivors who would experience CRCD after systematic treatment. Patients and Methods. We used the Thinking and Living with Cancer ...
Research Article
Financial-Legal navigation reduces financial toxicity of pediatric and AYA cancers
Jean Edward and others
Background Pediatric and Adolescent and Young Adult (AYA) cancer patients and caregivers are at high risk for financial toxicity and few evidence-based oncology financial and legal navigation programs exist to address it. We tested the feasibility, acceptability, and preliminary effectiveness of FINassist ( F inancial and I nsurance N avigation Assist ance ), a novel interdisciplinary financial ...
Brief Report
Tumor-Infiltrating lymphocytes and breast cancer mortality in racially and ethnically diverse participants of the Northern California breast cancer family registry
Julia D Ransohoff and others
Stromal tumor-infiltrating lymphocyte (sTIL) enrichment in pre-treatment breast tumors has been associated with superior response to neoadjuvant treatment and survival. In a population-based cohort, we studied sTIL-survival associations by race and ethnicity. We assessed associations of continuous sTIL scores and sTIL-enriched breast cancers (defined as percent lymphocytic infiltration of tumor ...
Brief Report
Racial differences in postpandemic trends in prostate-specific antigen screening
Zhiyu Qian and others
Our study investigates the trends in prostate cancer screening amid the COVID-19 pandemic, particularly focusing on racial disparities between Black and White men. Utilizing data from the Behavioral Risk Factor Surveillance System from 2018, 2020, and 2022, we analyzed prostate-specific antigen screening rates in men aged 45-75 years. Our findings reveal initial declines in screening rates for ...
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Indexing news

JNCI CS is proud to celebrate several recent milestone achievements. The journal successfully passed the review process for full deposit in PubMed Central, which means that all JNCI CS manuscripts are indexed and available in PubMed. JNCI CS has also been accepted for inclusion in MEDLINE. 

The journal has also recently been selected for the Emerging Sources Citation Index, which places it in the Web of Science Core Collection. 

From Dr Google to ChatGPT: are the tides turning in how cancer patients access information?

Dive into an exciting exploration of how ChatGPT “holds great potential to revolutionize how people seek health information”, courtesy of JNCI Cancer Spectrum author, Dr. Ashley Hopkins.

Read the post here.

JNCI Cancer Spectrum: Call For Papers

The Editors of JNCI Cancer Spectrum are calling for papers investigating how social determinants of health impact cancer care and outcomes, with particular interest in studies that involve clinical trials or prospective data collection.

Learn more here

Diversity, Equity, and Inclusion for the JNCI Journals

In 2022, the JNCI journals launched a DEI initiative, committing to increase diversity and inclusion of underrepresented groups in the peer review process and research dissemination. 1 year on, the teams provide an update. Read the editorial here. 

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Cancer patient or cancer survivor? Understanding illness identity.

Read a post on cancer survivorship written by JNCI Cancer Spectrum authors Dr. Melissa S. Y. Thong and Dr. Volker Arndt.

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