Objective: Neuropsychological deficits have been associated with alcoholism. Indeed, longitudinal research suggests that these deficits can be assessed prior to alcohol use onset and may represent an etiological factor. Developmental models of alcoholism recommend studying children of alcoholics (COAs) to better understand these precursor variables, as COAs are 2 to 5 times more likely to develop alcoholism as adults. Method: Eighty-three community-dwelling youth (ages 8 to 12) and their parents completed diagnostic screening interviews and a battery of executive functioning, as part of a larger longitudinal study funded by NIH RO1 AA020364 assessing the influence of sleep, parental substance use, and emotional functioning on youth development. Fifty-six subjects were identified as COAs. For the present study, Color-Word Interference (CWI) subtests of the Delis-Kaplan Executive Functioning System (DKEFS) were used. Results: A one-way MANOVA was conducted to compare higher-level neuropsychological functioning (i.e., contrast scaled scores of the CWI subtest) of COAs...

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