Objective: The C9ORF72 gene mutation is the most common form of familial frontotemporal dementia (FTD). Its clinical presentation is often associated with prominent psychotic symptoms, making it difficult to distinguish from very late onset psychotic disorders (VLOPD). Therefore, the objective of this case study is to highlight the neuropsychological differences that exist between C9ORF72 gene mutation FTD and VLOPD. Method: A 71-year-old female presented with a 2-year history of unusual beliefs and hallucinations. For example, she believed people were trespassing and stealing from her. She heard people knocking on her door and saw people looking through her windows. She had significant apathy and social withdrawal. PET scan results were inconclusive (i.e., atypical for FTD). Referral question asked for differential diagnosis between neurocognitive disorders and a psychiatric condition. Results: The cognitive profile revealed prominent deficits in language, frontally-mediated memory systems, and executive functions. Collateral informants endorsed moderate behaviour change including apathy,...

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