Objective: 1) To statistically analyze the precision gained by using the Neuropsychiatric Inventory (NPI) when measuring dementia of the Alzheimer's type (DAT). 2) To analyze relative precision gained across individual neuropsychiatric domains. Method: Demographic, neuropsychological and neuropsychiatric data for 906 participants were mined from the Alzheimer's Disease Neuroimaging Initiative (ADNI). We used Item Response Theory to define a latent DAT continuum, estimate model parameters, and quantify the measurement precision gained by individual and sets of NPI neuropsychiatric symptoms. Results: Results suggested that symptoms of delusions and hallucinations added the most precision, relative to all other neuropsychiatric symptoms. When including these symptoms, precision was gained primarily at relatively severe disease severity. Aberrant motor behavior had mild additive value, while all other symptoms had nearly no additive measurement value. Conclusion: Results indicate that that the NPI has additive assessment value for the measurement of DAT, particularly in at the relatively severe levels...

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