Objective: The comorbidity between Attention Deficit/Hyperactivity Disorder (ADHD) and depression has been consistently observed clinically and empirically in children. Reasoning that ADHD likely predates the onset of depression, it is important to identify modifiable intervening variables that might mitigate the severity of depression among children with ADHD. Children with ADHD also display deficits in adaptive skills. The present study hypothesized that adaptive skills would mediate the relationship between ADHD and depression. Method: The parents of a clinic-referred sample of 54 children (4-16 years old; 31% female; 82% Caucasian) completed the BASC-2 and Conners-3. Results: Results indicated adaptive skills significantly and fully mediated the relationship between ADHD inattentive symptoms and depressive symptoms (indirect effect = 0.20, SE = 0.08, p < 0.05, 95% CI = 0.07-0.39), such that the path from ADHD-inattentive to depression was no longer significant when adaptive skills were included in the model. In addition, mediation results also...

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