Objective: Multiple Sclerosis (MS) is an autoimmune condition of the central nervous system that has been associated with neuropsychological deficits in areas including executive functioning (EF). Generally, the association between results from performance-based measures and observable EF has been questioned due to concerns regarding ecological validity of EF measures. This association has not been explicitly studied in pediatric MS. The present objective is to investigate the association between EF test performance and observed EF behavioral ratings in a pediatric-onset MS sample. Method: Forty-six participants (mean age = 15.3 years) diagnosed with MS were administered a neuropsychological screening battery during a specialty clinic visit, including performance-based EF measures and parent version of the Behavioral Rating Inventory of Executive Function (BRIEF). Participants were at least 30 days from exacerbation and/or steroid use. Results: Correlation analyses revealed many statistically significant (p < .05) correlations between BRIEF rating scales Shift, Monitor, Planning/Organization, and Working...

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