Objective: The review examined the relationship between maternal, prenatal mental health stress and neurodevelopmental deficits. Data Selection: A systematic literature review was conducted using the following keywords: prenatal stress, neurodevelopmental disorders, neural activity, maternal mental health stress, maternal interpersonal stress, cognitive deficiencies. The following databases were used: PsychARTICLES, PsychINFO, PubMed, Academic OneFile, PsychARTICLES, MedLine., and only were included. Inclusion criteria was peer reviewed articles that examined the relationship between mental health prenatal stress and issues with neurodevelopment published in the last 10 years. Articles that only focused on maternal stress due to physiological or medical difficulties were excluded. Eleven studies met these criteria. Data Synthesis: Four studies, found a relationship between prenatal maternal stress and neurodevelopmental deficits related to the hypothalamic-pituitary-adrenal axis. Six studies, examined maternal stress using self-reports and physiological stress response measures revealed that prenatal stress was not limited in relation to prematurity and birth weight, but also...

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