Objective: To determine if sensory sensitivity severity was associated with changes in relative cerebral blood flow(rCBF) at baseline. Method: Data came from a de-identified SPECT database. Factor-analysis of a clinical intake assessment determined factors related to sensory sensitivity including sensitivity to light, noise, smell, touch and symptoms of restlessness, fatigue, and mood changes. MANOVA was used to determine differences in rCBF between “high” and “low” groups in 17 regions of interest (ROIs) in the brain at baseline. “High” (n = 2955; Mage = 41; 43%male; 70%Caucasian) and “low” (n = 3304; Mage = 41; 68%male; 69%Caucasian) severity groups were classified as the top and bottom quartiles of respondent sum scores, respectively. Results: At the .05 level significant differences were found between groups in Limbic-Left and Right(F = 103.41,F = 84.8),Basal Ganglia-Left and Right(F...

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