Objective: This case study examines a 15 year-old, right-handed Hispanic female diagnosed with Anti-N-methyl-d-aspartate receptor encephalitis (Anti-NMDAR-E), a rare life threatening condition. NMDA receptors are found in the forebrain, hypothalamus, and limbic system structures including hippocampus. Along with psychiatric symptoms, cognitive symptoms may include fast deterioration of short and long-term memory, attention, and executive functioning. Literature pertaining to neuropsychological sequelae of Anti-NMDAR-E is scarce. This case provides a more comprehensive understanding of how Anti-NMDAR-E impacts psychosocial and neurocognitive processes. Method: Two weeks prior to symptom onset, XX received a Menactra vaccine. Initial symptoms included confusion, hyperverbosity and incoherence alternating with stupor and mutism. Physically, she presented with lip smacking and hyper-perspiration. Behavior was characterized by restlessness, agitation, and aggression. Subsequently, she became catatonic with irregular vitals. Feelings of derealization, auditory hallucinations and paranoid...

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