Objective: This pilot study seeks to evaluate the effects of individualized cognitive remediation treatment on cognitive functioning with inpatient adolescents with persisting mental illness. Method: Five adolescent patients (2 males and 3 females), aged 12 to 16 years, with persisting mental illness, hospitalized at a state-run inpatient psychiatric facility were followed. Subjects received biweekly 30-minute sessions of individualized cognitive remediation therapy. All patients underwent a comprehensive neuropsychological evaluation prior to beginning cognitive remediation therapy and were re-assessed after approximately 16 weeks of treatment. Results: Our results demonstrated that three measures produced large pre- to post- effect sizes. These included total errors on the One-Back (d = -1.68) and Two-Back (d = -0.97) tasks as well as perseveration errors on the Groton Maze Learning task (d = -0.75). Moderate effect sizes were observed for Groton Maze Learning total errors (d = -0.67) and rule errors (d = -0.69), and on Groton...

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