Objective: Previous studies suggest that the effect of depression on cognition varies, in part due to whether the depression is being treated. This study examined the sensitivity of a computerized neuropsychological screening battery to detect cognitive differences associated with treated and untreated depression in adolescent athletes. We hypothesized that athletes with suspected depression would perform worse compared to non-depressed athletes, regardless of medication treatment status. Method: Participants were 168 student athletes ages 14-18 (mean age = 16.0, SD = 1.2; 83.3% female) divided into four equal groups (n = 42 each). The groups consisted of athletes with: (a) suspected depression, on antidepressants, (b) suspected depression, not on antidepressants, (c) on antidepressants, but not currently depressed, (d) and healthy controls. Participants were selected from a larger database of more than 30,000 youth, given the low incidence of depression, and matched on age, education, and gender. Suspected depression was defined as endorsing...

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