This paper overviews the current status of neuroimaging in neuropsychological outcome in traumatic brain injury (TBI). The pathophysiology of TBI is reviewed and integrated with expected neuroimaging and neuropsychological findings. The integration of clinical and quantitative magnetic resonance (QMR) imaging is the main topic of review, but these findings are integrated with single photon emission computed tomography (SPECT) and magnetoencephalography (MEG). Various clinical caveats are offered for the clinician.

Author notes

Much of the recent research reprinted in this article has been supported by grants from the Ira Fulton Foundation. The illustrations were prepared by Tracy Abildkov and manuscript preparation was assisted by Allison Neal.