Objective: To determine the feasibility and reliability of a brief battery of standard neuropsychological tests administered via videoconference to a sample of rural American Indians compared with traditional face-to-face-administration. Method: The sample consisted of 84 participants from the Choctaw Nation in Oklahoma, including 53 females and 31 males [M age = 64.89 (SD = 9.73), M education = 12.58 (SD = 2.35)]. Of these, 29 had a diagnosis of mild cognitive impairment or dementia, and 55 were cognitively normal. Test included the MMSE, Clock Drawing, Months forward and backward, Oral Trails, Hopkins Verbal Learning Task-Revised, Letter and Category Fluency, and a short form Boston Naming Test. Tests were administered in counterbalanced fashion in both face-to-face and videoconferencing conditions. Intraclass correlation coefficients (ICC) were performed to compare test scores between test conditions across the entire sample. Results: All ICCs were significant (p < .0001) and ranged from 0.65 (Clock Drawing) to 0.93 (Boston Naming Test), with a mean ICC of 0.80. Conclusion: Results add to the expanding literature supporting the feasibility and reliability of remote videoconference-based neuropsychological test administration and extend findings to rural American Indians.