To the Editor: I read with great interest the article by Dr Krajcoviechova and colleagues1 dealing with the relationship between serum uric acid and albuminuria in adults without full metabolic syndrome. The results of their study demonstrated that urine albumin/creatine ratio (uACR) was an independent factor for increase in uric acid levels only in persons with 1–2 metabolic syndrome components. It was also shown that uric acid levels increased by the interactions of uACR with visceral adiposity index (VAI). In addition, the association of uACR with uricemia was confined to persons whose VAI together with mean arterial pressure (MAP) were more than the median of 1.35 and 98 mm Hg, respectively. The authors have proposed a strong modification effect of VAI and MAP on the association between uACR and uricemia, which suggests obesity-related...

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