P-577: Blood pressure changes before during and after cigarette smoking in normal subjects:

Abstract

Cigarette smoking is an important risk factor for cardiovascular disease. Some studies have shown that smoking produces a acutely increase in Blood Pressure (BP), while other studies related the chronic effect of smoking with lower BP in smokers compared with nonsmokers. In Mexico don’t exist studies that demonstrate the acute effect of smoking in young adults with normal BP.

Determine Systolic Blood Pressure (SBP), Diastolic blood Pressure (DBP), Heart Rate (HR), and Pulse Pressure (PP), in smoking subjects before during and after cigarette smoking by Ambulatory Blood Pressure Monitoring (ABPM).

We included 56 smokers’ subjects and they were carried out an ABPM. The BP recording was made by 55 minutes, blood pressure readings were performed every five minutes; three blood pressure readings before smoking, one reading while they were smoking (they smoked by 5 minutes) and seven readings after smoking. The basal SBP, DBP, HR and PP refer to the previous registration to the beginning of smoking the cigarette (minute 0).

The mean age was 21.5 years (16-44 years). The most prevalent cardiovascular risk family history were Diabetes Mellitus (53%) and Hypertension (52%). Cigarette smoking was related to alcoholism in 64%. Five minutes after smoking SBP increased 8.5 mmHg (maximum peak) (7.5%), 10 minutes after smoking DBP increased 4.5 mmHg (maximum peak) (6%). Ten minutes after smoking HR increased 7.7 beats per minutes (bpm) (maximum peak, 9.8%). Basal PP was 39 mmHg, five minutes after smoking PP increased 4.5 mmHg (11.5%). The previous results were gotten in correlation with basal BP, HR and PP.

Cigarette smoking acutely increases BP, SBP is slightly higher than DBP this results in a increased PP. In the present study DBP and HR arisen after smoking was more gradual than SBP increase.

risk factor, smoking, blood pressure measurment