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Yoshiharu TAKAYAMA, Koko MIZUMACHI, Effect of Bovine Lactoferrin on Extracellular Matrix Calcification by Human Osteoblast-Like Cells, Bioscience, Biotechnology, and Biochemistry, Volume 72, Issue 1, 23 January 2008, Pages 226–230, https://doi.org/10.1271/bbb.70465
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Abstract
Osteoblast-mediated calcium deposition to the extracellular matrix (ECM) is a critical step in bone tissue generation. Bovine lactoferrin enhanced the calcium deposition by MG63 human osteoblast-like cells cultured on collagen-coated plates. Lactoferrin also promoted the alkaline phosphatase activity and osteocalcin production during the calcification process, whereas it had little effect on the growth of the cells on the collagen-coated plates.
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© Japan Society for Bioscience, Biotechnology, and Agrochemistry 2008
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