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Satoshi Tsuzuki, Takahiko Amitsuka, Tatsuya Okahashi, Yuki Kozai, Shigenobu Matsumura, Kazuo Inoue, Tohru Fushiki, A single aldehyde group can serve as a structural element for recognition by transmembrane protein CD36, Bioscience, Biotechnology, and Biochemistry, Volume 80, Issue 7, 2 July 2016, Pages 1375–1378, https://doi.org/10.1080/09168451.2016.1151343
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Abstract
Transmembrane protein CD36 is considered to bind its distinct ligands such as long-chain fatty acids primarily by recognizing their terminal carboxyl moiety. In this study, we provide evidence that long-chain fatty aldehydes, such as oleic aldehyde, can be recognized by CD36. We suggest that a single aldehyde group may also serve as one of the structural elements recognizable by CD36.
aldehyde functional group, CD36 ligands, fatty acid-related molecules, oleic aldehyde, receptor-binding moiety
© 2016 Japan Society for Bioscience, Biotechnology, and Agrochemistry
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