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Koji Masumura, Sachi Matsukami, Kumiko Yonekita, Muneyoshi Kanai, Kazunori Kume, Dai Hirata, Masaki Mizunuma, SKO1 deficiency extends chronological lifespan in Saccharomyces cerevisiae, Bioscience, Biotechnology, and Biochemistry, Volume 83, Issue 8, 3 August 2019, Pages 1473–1476, https://doi.org/10.1080/09168451.2019.1571901
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ABSTRACT
Sko1 plays a key role in the control of gene expression by osmotic and oxidative stress in yeast. We demonstrate that the decrease in chronological lifespan (CLS) of hog1Δ cells was suppressed by SKO1 deletion. sko1Δ single mutant cells were shown to have a longer CLS, thus implicating Sko1 in the regulation of their CLS.
© 2019 Japan Society for Bioscience, Biotechnology, and Agrochemistry
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