Abstract

Summary

Single-cell DNA template strand sequencing (Strand-seq) enables chromosome length haplotype phasing, construction of phased assemblies, mapping sister-chromatid exchange events and structural variant discovery. The initial quality control of potentially thousands of single-cell libraries is still done manually by domain experts. ASHLEYS automates this tedious task, delivers near-expert performance and labels even large data sets in seconds.

Availability and Implementation

github.com/friendsofstrandseq/ashleys-qc, MIT license

Supplementary information

Supplementary data are available at Bioinformatics online.

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Associate Editor: Pier Luigi Martelli
Pier Luigi Martelli
Associate Editor
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Supplementary data