Summary: The PPI3D web server is focused on searching and analyzing the structural data on protein–protein interactions. Reducing the data redundancy by clustering and analyzing the properties of interaction interfaces using Voronoi tessellation makes this software a highly effective tool for addressing different questions related to protein interactions.

Availability and Implementation: The server is freely accessible at http://bioinformatics.lt/software/ppi3d/.

Contact:ceslovas.venclovas@bti.vu.lt

Supplementary information:

are available at Bioinformatics online.

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