R/qtl: QTL mapping in experimental crosses

Abstract

Summary: R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and performing single-QTL and two-dimensional, two-QTL genome scans by multiple methods, with the possible inclusion of covariates.

Availability: The package is freely available at http://www.biostat.jhsph.edu/~kbroman/qtl.

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Present address: Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94143, USA.