Advance articles

Frailty and Cerebral Small Vessel Disease: A Cross-Sectional Analysis of the Tasmanian Study of Cognition and Gait (TASCOG)

Published: 2 August 2017 Section:  Research article

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Estimation of Skeletal Muscle Mass Relative to Adiposity Improves Prediction of Physical Performance and Incident Disability

Published: 29 July 2017 Section:  Research article

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Cross-Sectional and Longitudinal Relationships Between Inflammatory Biomarkers and Frailty in Community-dwelling Older Men: The Concord Health and Ageing in Men Project

Published: 28 July 2017 Section:  Research article

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Cognitive Function and Changes in Cognitive Function as Predictors of Incident Cardiovascular Disease: The Women’s Health Initiative Memory Study

Published: 25 July 2017 Section:  Research article

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FNIH-defined Sarcopenia Predicts Adverse Outcomes Among Community-dwelling Older People in Taiwan: Results from the I-Lan Longitudinal Aging Study

Published: 25 July 2017 Section:  Research article

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Measures of Biologic Age in a Community Sample Predict Mortality and Age-related Disease: The Framingham Offspring Study

Published: 25 July 2017 Section:  Research article

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Nutritional supplementation with physical activity improves muscle composition in mobility-limited older adults, the VIVE2 study: a randomized, double-blind, placebo-controlled trial

Published: 25 July 2017 Section:  Research article

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Plasma Sphingolipids are Associated With Gait Parameters in the Mayo Clinic Study of Aging

Published: 25 July 2017 Section:  Research article

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Men sustain higher dysregulation levels than women without becoming frail

Published: 23 July 2017 Section:  Original Article

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Trajectories of IGF-I Predict Mortality in Older Adults: the Cardiovascular Health Study

Published: 23 July 2017 Section:  Research article

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Is There a Link Between Cognitive Reserve and Cognitive Function in the Oldest-Old?

Published: 22 July 2017 Section:  Research article

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Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies

Published: 18 July 2017 Section:  Original Article

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Allogeneic Mesenchymal Stem Cells Ameliorate Aging Frailty A phase II randomized, double-blinded, placebo controlled clinical trial

Published: 17 July 2017 Section:  Research article

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Caloric Restriction Study Design Limitations in Rodent and Nonhuman Primate Studies

Published: 8 July 2017 Section: 

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3β-Hydroxy-urs-12-en-28-oic Acid Modulates Dietary Restriction Mediated Longevity and Ameliorates Toxic Protein Aggregation in C. elegans

Published: 30 June 2017 Section:  Original Article

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Centenarians Differ in Their Comorbidity Trends During The 6 Years Before Death Compared to Individuals Who Died in Their 80s or 90s

Published: 29 June 2017 Section:  Research article

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Cellular Senescence Biomarker p16^INK4a+ Cell Burden in Thigh Adipose is Associated With Poor Physical Function in Older Women

Published: 27 June 2017 Section:  Research article

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Physical Activity in Older Adults With Mild Parkinsonian Signs: A Cohort Study

Published: 27 June 2017 Section:  Research article

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Proteins Involved in Endocytosis Are Upregulated by Ageing in the Normal Human Brain: Implications for the Development of Alzheimer’s Disease

Published: 26 June 2017 Section:  Original Article

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Evaluating Accelerometry Thresholds for Detecting Changes in Levels of Moderate Physical Activity and Resulting Major Mobility Disability

Published: 24 June 2017 Section:  Research article

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Sex-dependent Differences in Liver and Gut Metabolomic Profiles With Acarbose and Calorie Restriction in C57BL/6 Mice

Published: 23 June 2017 Section:  Original Article

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Longitudinal associations between walking speed and amount of self-reported time spent walking over a 9-year period in older women and men

Published: 22 June 2017 Section:  Research article

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IGF-I Gene Therapy in Aging Rats Modulates Hippocampal Genes Relevant to Memory Function

Published: 22 June 2017 Section:  Original Article

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Effects of Mobility and Multimorbidity on Inpatient and Postacute Health Care Utilization

Published: 22 June 2017 Section:  Research article

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Associations Between Vitamin D Levels and Depressive Symptoms in Later Life: Evidence From the English Longitudinal Study of Ageing (ELSA)

Published: 22 June 2017 Section:  Research article

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Dissociation of Striatal Dopamine and Tyrosine Hydroxylase Expression from Aging-Related Motor Decline: Evidence from Calorie Restriction Intervention

Published: 20 June 2017 Section:  Original Article

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Low Alanine Aminotransferase Levels in the Elderly Population: Frailty, Disability, Sarcopenia, and Reduced Survival

Published: 19 June 2017 Section:  Research article

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Mobility Difficulties, Physical Activity, and All-cause Mortality Risk in a Nationally representative Sample of Older Adults

Published: 19 June 2017 Section:  Research article

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High Intensity Interval Training Improves Physical Performance and Frailty in Aged Mice

Published: 17 June 2017 Section:  Original Article

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Association Between Subjective Sleep Quality and Future Risk of Falls in Older People: Results From LOHAS

Published: 17 June 2017 Section:  Research article

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Physical Activity Attenuates Total and Cardiovascular Mortality Associated With Physical Disability: A National Cohort of Older Adults

Published: 16 June 2017 Section:  Research article

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Response to “Motor Output Variability Impairs Driving Ability in Older Adults”

Published: 14 June 2017 Section:  Letter to the Editor

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Motor Output Variability Impairs Driving Ability in Older Adults: Reply to Stinchcombe, Dickerson, Weaver, and Bedard

Published: 14 June 2017 Section:  Response to Letter to Editor

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Cognitive Trajectories of Older Adults With Prediabetes and Diabetes: A Population-Based Cohort Study

Published: 13 June 2017 Section:  Research article

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Caloric Restriction Study Design Limitations in Rodent and Nonhuman Primate Studies

Published: 13 June 2017 Section:  Special issue: Caloric Restriction and Restrictive Diets: Interventions that Target the Biology of Aging: Original Article

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Changes in Everyday and Digital Health Technology Use Among Seniors in Declining Health

Published: 12 June 2017 Section:  Research article

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What Explains Socioeconomic Differences in the Speed of Heart Rate Recovery to Postural Challenge?

Published: 9 June 2017 Section:  Corrigendum

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Risk Profiles for Injurious Falls in People Over 60: A Population-Based Cohort Study

Published: 9 June 2017 Section:  Research article

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Multimorbidity and Physical and Cognitive Function: Performance of a New Multimorbidity-Weighted Index

Published: 9 June 2017 Section:  Research Practice

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Improvement in Activities of Daily Living Among Danish Centenarians?—A Comparative Study of Two Centenarian Cohorts Born 20 Years Apart

Published: 8 June 2017 Section:  Research article

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A Randomized Controlled Pilot Trial of Interventions to Improve Functional Recovery After Hospitalization in Older Adults: Feasibility and Adherence

Published: 7 June 2017 Section:  Research article

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Combined Plasma Elevation of CRP, Intestinal-Type Fatty Acid-Binding Protein (I-FABP), and sCD14 Identify Older Patients at High Risk for Health Care-Associated Infections

Published: 3 June 2017 Section:  Research article

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Subclinical Cardiovascular Disease and Changes in Self-Reported Mobility: Multi-Ethnic Study of Atherosclerosis

Published: 3 June 2017 Section:  Research article

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Role of cell-intrinsic and environmental age-related changes in altered maintenance of murine T cells in lymphoid organs

Published: 3 June 2017 Section:  Research article

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Corrigendum

Published: 2 June 2017 Section:  Corrigendum

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Sex Differences in Aging: Genomic Instability

Published: 2 June 2017 Section:  Special Issue: Sex, Gender and Aging: Review in Depth

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Fisetin Reduces the Impact of Aging on Behavior and Physiology in the Rapidly Aging SAMP8 Mouse

Published: 2 June 2017 Section:  Original Article

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Adverse Childhood Experiences and Higher-Level Functional Limitations Among Older Japanese People: Results From the JAGES Study

Published: 2 June 2017 Section:  Research article

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Physical Resilience: Opportunities and Challenges in Translation

Published: 30 May 2017 Section:  Corrigendum

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The Effects of Graded Levels of Calorie Restriction: X. Transcriptomic Responses of Epididymal Adipose Tissue

Published: 27 May 2017 Section:  Original Article

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Longitudinal Associations Between Vitamin D Metabolites and Sarcopenia in Older Australian men: The Concord Health and Aging in Men Project

Published: 25 May 2017 Section:  Research article

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High-Protein Foods and Physical Activity Protect Against Age-Related Muscle Loss and Functional Decline

Published: 25 May 2017 Section:  Research article

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Prospective Disability in Different Combinations of Somatic and Mental Multimorbidity

Published: 24 May 2017 Section:  Research article

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Prevalence and Co-Occurrence of Geriatric Syndromes in People Aged 75 Years and Older in France: Results From the Bordeaux Three-city Study

Published: 24 May 2017 Section:  Research article

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Effects of Calorie Restriction and Fiber Type on Glucose Uptake and Abundance of Electron Transport Chain and Oxidative Phosphorylation Proteins in Single Fibers from Old Rats

Published: 22 May 2017 Section:  Original Article

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Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis

Published: 22 May 2017 Section:  Special issue: Caloric Restriction and Restrictive Diets: Interventions that Target the Biology of Aging: Original Article

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Prevalence and Correlates of Frailty Among Community-Dwelling Chinese Older Adults: The China Health and Retirement Longitudinal Study

Published: 19 May 2017 Section:  Research article

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Sexual Dimorphism and Aging Differentially Regulate Adaptive Homeostasis

Published: 18 May 2017 Section:  Special Issue: Sex, Gender and Aging: Review in Depth

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Impact of Aging on Calcium Signaling and Membrane Potential in Endothelium of Resistance Arteries: A Role for Mitochondria

Published: 16 May 2017 Section:  Original Article

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Telomeres, Nutrition, and Longevity: Can We Really Navigate Our Aging?

Published: 16 May 2017 Section:  Special Issue: Caloric Restriction and Restrictive Diets: Interventions that Target the Biology of Aging: Review in Depth

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Diabetes and Cognitive Decline in Older Adults: The Ginkgo Evaluation of Memory Study

Published: 16 May 2017 Section:  Research article

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Resveratrol Enhances Exercise-Induced Cellular and Functional Adaptations of Skeletal Muscle in Older Men and Women

Published: 13 May 2017 Section:  Original Article

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Associations of Musculoskeletal Pain With Mobility in Older Adults: Potential Cerebral Mechanisms

Published: 13 May 2017 Section:  Research article

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Comparison of the Simplified sWHI and the Standard CHS Frailty Phenotypes for Prediction of Mortality, Incident Falls, and Hip Fractures in Older Women

Published: 13 May 2017 Section:  Research article

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Sex Differences in Risk for Alzheimer’s Disease Related to Neurotrophin Gene Polymorphisms: The Cache County Memory Study

Published: 12 May 2017 Section:  Original Article

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The Intersection Of Aging Biology and The Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop

Published: 12 May 2017 Section:  Original Article

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Expression and activity of the small RhoGTPase Cdc42 in blood cells of older adults are associated with age and cardiovascular disease

Published: 12 May 2017 Section:  Brief Report

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Genetic Predisposition to Obesity and Medicare Expenditures

Published: 10 May 2017 Section:  Research article

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Activation-Induced Autophagy Is Preserved in CD4⁺ T-Cells in Familial Longevity

Published: 9 May 2017 Section:  Brief Report

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Apolipoprotein E4 Allele and Gait Performance in Mild Cognitive Impairment: Results From the Gait and Brain Study

Published: 6 May 2017 Section:  Research article

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Polypharmacy as a Risk Factor for Clinically Relevant Sarcopenia: Results From the Berlin Aging Study II

Published: 6 May 2017 Section:  Research article

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Stabilized Incidence in Proximal Humeral Fractures of Elderly Women: Nationwide Statistics From Finland in 1970–2015

Published: 5 May 2017 Section:  Research article

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Intermediate, But Not Extended, Afternoon Naps May Preserve Cognition in Chinese Older Adults

Published: 5 May 2017 Section:  Research article

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Gait Rather Than Cognition Predicts Decline in Specific Cognitive Domains in Early Parkinson’s Disease

Published: 3 May 2017 Section:  Research article

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Do Female Dogs Age Differently Than Male Dogs?

Published: 2 May 2017 Section:  Original Article

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Financial Exploitation Is Associated With Structural and Functional Brain Differences in Healthy Older Adults

Published: 2 May 2017 Section:  Brief Report

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Association Between Adherence to the Mediterranean Diet at Midlife and Healthy Aging in a Cohort of French Adults

Published: 29 April 2017 Section:  Research article

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Digital PCR Quantitation of Muscle Mitochondrial DNA: Age, Fiber Type, and Mutation-Induced Changes

Published: 29 April 2017 Section:  Original Article

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Executive Network Activation is Linked to Walking Speed in Older Adults: Functional MRI and TCD Ultrasound Evidence From the MOBILIZE Boston Study

Published: 26 April 2017 Section:  Research article

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Biological Aging and the Human Gut Microbiota

Published: 25 April 2017 Section:  Original Article

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Allogeneic Human Mesenchymal Stem Cell Infusions for Aging Frailty

Published: 21 April 2017 Section:  Research article

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Clinically Relevant Cut-off Points for the Diagnosis of Sarcopenia in Older Korean People

Published: 21 April 2017 Section:  Research article

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What Explains Socioeconomic Differences in the Speed of Heart Rate Recovery to Postural Challenge?

Published: 12 April 2017 Section:  Research article

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Effects of Low Muscle Mass on Albuminuria and Chronic Kidney Disease in Patients With Type 2 Diabetes: The Korean Sarcopenic Obesity Study (KSOS)

Published: 12 April 2017 Section:  Research article

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Caloric Restriction and Healthy Life Span: Frail Phenotype of Nonhuman Primates in the Wisconsin National Primate Research Center Caloric Restriction Study

Published: 8 April 2017 Section:  Special issue: Caloric Restriction and Restrictive Diets: Interventions that Target the Biology of Aging: Original Article

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Change in Bone Mineral Density During Weight Loss with Resistance Versus Aerobic Exercise Training in Older Adults

Published: 3 April 2017 Section:  Brief Report

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Association of Family History of Exceptional Longevity With Decline in Physical Function in Aging

Published: 1 April 2017 Section:  Research article

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A 2-Year Follow-Up After a 2-Year RCT with Vitamin D and Exercise: Effects on Falls, Injurious Falls and Physical Functioning Among Older Women

Published: 21 March 2017 Section:  Research article

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Life-Span Extension by Axenic Dietary Restriction Is Independent of the Mitochondrial Unfolded Protein Response and Mitohormesis in Caenorhabditis elegans

Published: 17 March 2017 Section:  Original Article

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Resveratrol Improves Vascular Function and Mitochondrial Number but Not Glucose Metabolism in Older Adults

Published: 16 March 2017 Section:  Research article

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Four Genome-Wide Association Studies Identify New Extreme Longevity Variants

Published: 15 March 2017 Section:  Original Article

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Prediction of Long-term Cognitive Decline Following Postoperative Delirium in Older Adults

Published: 15 March 2017 Section:  Research article

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Body Mass Index and Waist Circumference as Predictors of Disability in Nonagenarians: The Vitality 90+ Study

Published: 14 March 2017 Section:  Research article

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Kidney Function Estimated From Cystatin C, But Not Creatinine, Is Related to Objective Tests of Physical Performance in Community-Dwelling Older Adults

Published: 10 March 2017 Section:  Research article

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Age-Related Biomarkers in LLFS Families With Exceptional Cognitive Abilities

Published: 10 March 2017 Section:  Research article

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Low Normalized Grip Strength is a Biomarker for Cardiometabolic Disease and Physical Disabilities Among U.S. and Chinese Adults

Published: 10 March 2017 Section:  Research article

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Comprehensive miRNA Profiling of Skeletal Muscle and Serum in Induced and Normal Mouse Muscle Atrophy During Aging

Published: 10 March 2017 Section:  Original Article

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Association of Accelerometer-Measured Physical Activity With Leukocyte Telomere Length Among Older Women

Published: 9 March 2017 Section:  Research article

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Caloric Restriction and Rapamycin Differentially Alter Energy Metabolism in Yeast

Published: 8 March 2017 Section:  Original Article

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Caloric Restriction Mimetics Slow Aging of Neuromuscular Synapses and Muscle Fibers

Published: 7 March 2017 Section:  Original Article

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