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Migraine is considered to be a common disabling primary headache disorder. It has a high prevalence with epidemiological studies documenting high socio-economic and personal impact. It is one of the most common clinical presentations to neurologists in routine practice. In a systematic analysis of Global Burden of Disease Study 2010,1 it was found that migraine is the seventh most common cause globally of years lived with disability with a global prevalence of 14.7% and nearly 3% worldwide disability attributable to any specific disease. Migraine is about twice as common in women (12–14%) than men (6–8%). If untreated, the median duration of a migraine attack is 18 h with the median attack frequency 1 per month. In Europe, 12–28% of...

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