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Neurodegeneration - Cellular & Molecular
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Journal Article

Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levels

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Yo-El S. Ju, Sharon J. Ooms, Courtney Sutphen, Shannon L. Macauley, Margaret A. Zangrilli ...
Published: 10 July 2017
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EDITOR'S CHOICE

The Alzheimer’s disease transcriptome mimics the neuroprotective signature of IGF-1 receptor-deficient neurons

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Caroline George, Géraldine Gontier, Philippe Lacube, Jean-Christophe François, Martin Holzenberger ...
Published: 08 June 2017
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Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice

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Mark Halliday, Helois Radford, Karlijn A. M. Zents, Collin Molloy, Julie A. Moreno ...
Published: 19 April 2017
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Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

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Hugo Vicente Miranda, Éva M. Szegő, Luís M. A. Oliveira, Carlo Breda, Ekrem Darendelioglu ...
Published: 10 April 2017
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EDITOR'S CHOICE

Biochemically-defined pools of amyloid-β in sporadic Alzheimer’s disease: correlation with amyloid PET

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Blaine R. Roberts, Monica Lind, Aaron Z. Wagen, Alan Rembach, Tony Frugier ...
Published: 05 April 2017
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Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model

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Rebecca M. Nisbet, Ann Van der Jeugd, Gerhard Leinenga, Harrison T. Evans, Phillip W. Janowicz ...
Published: 04 April 2017
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Insulin resistance and exendin-4 treatment for multiple system atrophy

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Fares Bassil, Marie-Hélène Canron, Anne Vital, Erwan Bezard, Yazhou Li ...
Published: 14 March 2017
Journal Article

A combinatorial approach to identify calpain cleavage sites in the Machado-Joseph disease protein ataxin-3

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Jonasz J. Weber, Matthias Golla, Giambattista Guaitoli, Pimthanya Wanichawan, Stefanie N. Hayer ...
Published: 08 March 2017
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EDITOR'S CHOICE

C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia

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Yoshitsugu Aoki, Raquel Manzano, Yi Lee, Ruxandra Dafinca, Misako Aoki ...
Published: 23 February 2017
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EDITOR'S CHOICE

A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction

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Ana Lopez, Suzee E. Lee, Kevin Wojta, Eliana Marisa Ramos, Eric Klein ...
Published: 09 February 2017
Journal Article

Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer’s disease mice

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Sandro Alves, Guillaume Churlaud, Mickael Audrain, Kristin Michaelsen-Preusse, Romain Fol ...
Published: 20 December 2016
Journal Article

Unbiased screen identifies aripiprazole as a modulator of abundance of the polyglutamine disease protein, ataxin-3

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Maria do Carmo Costa, Naila S. Ashraf, Svetlana Fischer, Yemen Yang, Emily Schapka ...
Published: 19 September 2016
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The yin and yang of α-synuclein-associated epigenetics in Parkinson’s disease

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Maria Angeliki S. Pavlou, Raquel Pinho, Isabel Paiva, Tiago Fleming Outeiro
Published: 31 August 2016
Journal Article

LIN28A enhances the therapeutic potential of cultured neural stem cells in a Parkinson’s disease model

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Yong-Hee Rhee, Tae-Ho Kim, A.-Young Jo, Mi-Yoon Chang, Chang-Hwan Park ...
Published: 18 August 2016
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Mislocated FUS is sufficient for gain-of-toxic-function amyotrophic lateral sclerosis phenotypes in mice

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Gen Shiihashi, Daisuke Ito, Takuya Yagi, Yoshihiro Nihei, Taeko Ebine ...
Published: 30 June 2016
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EDITOR'S CHOICE

Tauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate

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Marie K. Bondulich, Tong Guo, Christopher Meehan, John Manion, Teresa Rodriguez Martin ...
Published: 11 June 2016
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EDITOR'S CHOICE

Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer’s disease model mice

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Nathaniel S. Woodling, Nathaniel S. Woodling, Damien Colas, Damien Colas, Qian Wang ...
Published: 13 May 2016
Journal Article

The unfolded protein response: mechanisms and therapy of neurodegeneration

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Heather L. Smith, Giovanna R. Mallucci
Published: 11 May 2016
Journal Article

Thalamic pathology and memory loss in early Alzheimer’s disease: moving the focus from the medial temporal lobe to Papez circuit

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John P. Aggleton, Agathe Pralus, Andrew J. D. Nelson, Michael Hornberger
Published: 28 April 2016
Journal Article

Motor neuron degeneration in spastic paraplegia 11 mimics amyotrophic lateral sclerosis lesions

Paola S. Denora, Katrien Smets, Federica Zolfanelli, Chantal Ceuterick-de Groote, Carlo Casali ...
Published: 25 March 2016