
Published online:
22 March 2012
Published in print:
12 March 2009
Online ISBN:
9780520944473
Print ISBN:
9780520247666
Contents
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Evolutionary Theories of Aging Evolutionary Theories of Aging
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Hamilton’s Forces of Natural Selection Hamilton’s Forces of Natural Selection
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Comparative Biology of Aging Comparative Biology of Aging
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Specific Population Genetic Hypotheses for Aging Specific Population Genetic Hypotheses for Aging
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Antagonistic Pleiotropy Antagonistic Pleiotropy
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Mutation Accumulation Mutation Accumulation
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Large-Effect Mutants and the Genetics of Aging Large-Effect Mutants and the Genetics of Aging
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The Role of Experimental Evolution in Testing Hamiltonian Theories of Aging The Role of Experimental Evolution in Testing Hamiltonian Theories of Aging
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Laboratory Evolution of Aging Laboratory Evolution of Aging
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Experimental Population Genetics of Aging Experimental Population Genetics of Aging
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Correlation between Relatives Correlation between Relatives
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Indirect Responses to Selection Indirect Responses to Selection
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Varying Extrinsic Mortality Rates Varying Extrinsic Mortality Rates
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The Number of Genes Affecting Aging The Number of Genes Affecting Aging
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Evolutionary Biology of Late Life Evolutionary Biology of Late Life
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The Discovery of Late Life The Discovery of Late Life
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Explaining Late Life with Hamiltonian Theory Explaining Late Life with Hamiltonian Theory
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Plateaus in the Forces of Natural Selection Plateaus in the Forces of Natural Selection
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Explaining Late Life with Nonevolutionary Theories Explaining Late Life with Nonevolutionary Theories
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Experimentally Testing Hamiltonian Theories of Late Life Experimentally Testing Hamiltonian Theories of Late Life
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Basic Predictions of the Hamiltonian Theory of Late Life Basic Predictions of the Hamiltonian Theory of Late Life
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Mortality Mortality
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Fecundity Fecundity
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Population Genetic Mechanisms of Late-Life Evolution Population Genetic Mechanisms of Late-Life Evolution
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Experimentally Testing Nonevolutionary Theories of Late Life Experimentally Testing Nonevolutionary Theories of Late Life
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Mortality Mortality
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Fecundity Fecundity
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Are We Needlessly Cruel? Are We Needlessly Cruel?
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The Impact of Experimental Evolution on Aging Research The Impact of Experimental Evolution on Aging Research
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Summary Summary
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Acknowledgments Acknowledgments
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References References
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Chapter
18 Evolution of Aging and Late Life
Get access
Pages
551–584
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Published:March 2009
Cite
Rauser, Casandra L., and others, 'Evolution of Aging and Late Life ', in Theodore (ed.), Experimental Evolution: Concepts, Methods, and Applications of Selection Experiments (Oakland, CA , 2009; online edn, California Scholarship Online, 22 Mar. 2012), https://doi.org/10.1525/california/9780520247666.003.0018, accessed 19 Apr. 2025.
Abstract
Aging, like all biological characters, evolves. From an evolutionary point of view, it can be defined as a sustained age-specific decline of fitness-related characteristics that is not due to external environmental factors. This chapter discusses the evolutionary theories of aging and the experimental studies that have tested and challenged them, and also discusses the postaging phase of life, referred to as “late life,” and the experimental and theoretical work surrounding this phenomenon.
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