Free fatty acids and arrhythmias following acute coronary artery occlusion in pigs

MOST, A. S.; CAPONE, R. J.; MASTROFRANCESCO, P. A.

doi:10.1093/cvr/11.3.198

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Free fatty acids and arrhythmias following acute coronary artery occlusion in pigs

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SUMMARY

The arrhythmogenic potential of elevated serum free fatty acids (FFA) was investigated in closed-chest pigs following acute coronary artery occlusion. Animals both with and without ventricular irritability before the FFA rise were studied. No significant increase in PVC frequency occurred and only 1 out of 17 animals developed ventricular fibrillation in the 60min following acute FFA elevation. In this situation, FFA did not significantly influence the appearance of arrhythmias.

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Free fatty acids and arrhythmias following acute coronary artery occlusion in pigs

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Free fatty acids and arrhythmias following acute coronary artery occlusion in pigs

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