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Stem cells and tissue engineering

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Stem cell highways: signalling beats trafficking?

Sampaolesi, Maurilio, Cardiovasc Res (2013) 100(2) doi: 10.1093/cvr/cvt221 - Click here to view the abstract 

SDF-1α/CXCR4 cellular highway. Chemokines control cellular traffic by directing cells that express certain chemokine receptors to specific locations where their ligands are abundant. Besides PCs (circulating progenitor cells) other stem cell types could be recruited in specific cellular highways according to their chemokine receptor expression. ESCs, embryonic stem cells; iPSCs, induced pluripotent stem cells; MABs, mesoangioblasts; MADS, multipotent adipose-derived stem cells.

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