The Infection-Free Interval: Its Use in Evaluating Antimicrobial Treatment of Acute Exacerbation of Chronic Bronchitis

Department of Pulmonary Medicine and Critical Care, The University of Texas Health Science Center at San Antonio, San Antonio, Texas; Department of Epidemiology and Public Health, Division of Health Policy and Administration, Yale University School of Medicine, New Haven, Connecticut; and the University of Toronto and Mt. Sinai Hospital, Toronto, Ontario, Canada

Department of Pulmonary Medicine and Critical Care, The University of Texas Health Science Center at San Antonio, San Antonio, Texas; Department of Epidemiology and Public Health, Division of Health Policy and Administration, Yale University School of Medicine, New Haven, Connecticut; and the University of Toronto and Mt. Sinai Hospital, Toronto, Ontario, Canada

Department of Pulmonary Medicine and Critical Care, The University of Texas Health Science Center at San Antonio, San Antonio, Texas; Department of Epidemiology and Public Health, Division of Health Policy and Administration, Yale University School of Medicine, New Haven, Connecticut; and the University of Toronto and Mt. Sinai Hospital, Toronto, Ontario, Canada