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Volume 2017, Issue 1
January 2017
EISSN 2050-6201
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Original Research Article

Gene drive has come of age with advances in genetic engineering. An unresolved question is whether gene drive systems will achieve population suppression or will instead succumb to resistance in the target population. Here is it shown that the evolution of inbreeding can be favored in response to a gene drive system, substantially reducing its efficacy.

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