Andrea C. Gore, PhD, and Stephen R. Hammes, MD, PhD
About the journal
Endocrinology: Molecular and Physiological Basis of Endocrine Health and Disease is the premier basic science journal of the Endocrine Society, publishing basic and translational research at molecular, biochemical, cellular, genomic, comparative, and organismal levels since 1917.
Drs. Gore and Hammes have selected additional research articles as Editor’s Choice in the latest issue of Endocrinology. Find out more.
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Circulating Insulin-Like Growth Factor I Regulates Its Receptor in the Brain of Male Mice
The activity-dependent entrance of serum IGF-I into the brain results in tight modulation of brain IGF-I receptor levels to spatio-temporally restrict its own actions in the brain. Read more.
A Thalamo-Hypothalamic Pathway That Activates Oxytocin Neurons in Social Contexts in Female Rats
A group of posterior thalamic neurons is activated by pups in mothers and also in familiar females. These neurons are excitatory, receive ascending afferent connections, and project to the PVN to innervate oxytocin neurons. Read more.
The Steroidogenic Acute Regulatory Protein (StAR) Is Regulated by the H19/let-7 Axis
Overexpression of the lncRNA H19 stimulates StAR expression by antagonizing let-7 (which itself inhibits StAR at the posttranscriptional level). These results uncover a novel mechanism underlying the regulation of StAR expression and represent the first example of lncRNA-mediated control of the rate-limiting step of steroidogenesis. Read more.
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