Testosterone and Dihydrotestosterone Concentrations in Plasma, Epididymal Tissues, and Seminal Fluid of Adult Rats

PUJOL, ANDRÉ; BAYARD, FRANCIS; LOUVET, JEAN-PIERRE; BOULARD, CLAUDE

doi:10.1210/endo-98-1-111

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Testosterone and Dihydrotestosterone Concentrations in Plasma, Epididymal Tissues, and Seminal Fluid of Adult Rats

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The concentration of testosterone (T) and 5α-dihydrotestosterone (DHT)^* in plasma, seminal fluid, and epididymis ofmale Wistar rats have been determined by radioimmunoassay. The DHT/T ratio rose from 0.1 in blood to 1 in testicular fluid and 4 in epididymal fluid. This ratio is 2 in tissues of “caput” epididymis and 1 in “cauda” epididymis. These data indicate a transformation of T to DHT in the epididymal tissue, particularly at the “caput” level. (Endocrinology98: 105, 1976)

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Testosterone and Dihydrotestosterone Concentrations in Plasma, Epididymal Tissues, and Seminal Fluid of Adult Rats

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Testosterone and Dihydrotestosterone Concentrations in Plasma, Epididymal Tissues, and Seminal Fluid of Adult Rats

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