The impact of COVID-19 on persons with concurrent mental health and substance use disorders

Abstract Background The COVID-19 pandemic with its restrictions touched the daily life of most people. While everyday social life becomes difficult for citizens with economic and cultural capital, it becomes even worse for persons with mental health (MHD) and substance use disorders (SUD), who are particularly vulnerable to social exclusion. In this project, we aim to explore the impact of the pandemic on persons MHD/SUD, nearer, how the lockdown effected their daily life and further, the utilization of health care services under the consecutive waves of the pandemic. Methods The project has two parts: First we conducted 17 individual interviews and one focus group with persons with MHD/SUD, using thematic analysis. Second, we merged the Norwegian Patient Register, the Register for Infectious Diseases and data from Statistics Norway. We matched data of 41500 individuals with MHD/SUD after gender, age and health region with a sample from the general population as a control group and study the health care service utilization under the consecutive waves of the pandemic in Norway in 2020-2021. Results Within the qualitative study, we identified four interrelated main themes: (1) The COVID-19 outbreak as a perceived challenge, (2) A decline in mental health and well-being, (3) Increased substance use challenges, and (4) Diverse experiences with health and social services. The results show further that people with MHD/SUD have challenges with digital tools and/or do not have the appropriate equipment. Persons with MHD/SUD face greater barriers in accessing the health care system compared to the general population as a control group. Results of the register study are still preliminary. Conclusions Persons with MHD/SUD face major challenges during the COVID-19 pandemic There is reason to believe that new pandemics will emerge in the future. In this context, it is essential to gain knowledge of how to care for vulnerable groups in society and how to reach them in emergencies. Key messages • Continuous maintenance of low-threshold services for persons with MHD/SUD during a pandemic is essential. • Improvement of digital skills of service users or alternatives to digital consultations should be considered.

Nationally published COVID-19 mortality estimates might underestimate the actual mortality burden attributed to . Estimations of excess all-cause mortality can provide more accurate estimates of the toll of the pandemic. This study aims to estimate the overall, sex and age-specific excess all-cause mortality in 20 countries, during 2020. Total, sex and age-specific weekly all-cause death counts for 2015-2020 were extracted from national vital statistics databases. Percent excess mortality for 2020 was calculated by comparing average weekly 2020 mortality rates against average weekly mortality rates from the past five years (2015)(2016)(2017)(2018)(2019). Comparisons were performed for the total population, per sex, and per age groups (<65 vs. 65+ or < 70 vs.70+) depending on data availability. Percent difference in average weekly mortality between 2020 and 2015-2019 ranged from negative for Australia and Norway, to < 5% for Denmark, Cyprus, Estonia, Israel, and Sweden, 5-10% for Georgia, Mauritius, Ukraine, Austria, France, Scotland and Northern Ireland, to 10-21% for England & Wales, Italy, Brazil, USA, Slovenia, and to 89% for Peru. The percent difference in average weekly mortality between 2020 and 2015-2019 for males was higher than for females except for Cyprus, Estonia, Slovenia and the USA. Lastly, in age specific analyses, for the majority of countries the % increase in average weekly mortality between 2020 and 2015-2019, was higher in the oldest age group investigated, however, for Peru and the USA (<65 vs. 65+ years) and for Cyprus and Mauritius (<70 vs. 70+ years), mortality increased similarly in both age groups. This study highlights that the excess mortality burden during the COVID-19 pandemic disproportionally affected specific countries, males, and in most, but not all countries, the oldest age groups. Strengthening of health resilience in the most affected countries, while targeting population groups impacted the most, is of paramount public health importance.

Key messages:
Excess mortality burden during the COVID-19 pandemic disproportionally affected specific countries, and even within countries specific sex and age groups. Further investigation into the determinants of excess mortality is needed to suggest steps to strengthen health resilience in the countries and target population groups impacted the most.
becomes even worse for persons with mental health (MHD) and substance use disorders (SUD), who are particularly vulnerable to social exclusion. In this project, we aim to explore the impact of the pandemic on persons MHD/SUD, nearer, how the lockdown effected their daily life and further, the utilization of health care services under the consecutive waves of the pandemic.

Methods:
The project has two parts: First we conducted 17 individual interviews and one focus group with persons with MHD/SUD, using thematic analysis. Second, we merged the Norwegian Patient Register, the Register for Infectious Diseases and data from Statistics Norway. We matched data of 41500 individuals with MHD/SUD after gender, age and health region with a sample from the general population as a control group and study the health care service utilization under the consecutive waves of the pandemic in Norway in 2020-2021.

Results:
Within the qualitative study, we identified four interrelated main themes: (1) The COVID-19 outbreak as a perceived challenge, (2) A decline in mental health and well-being, (3) Increased substance use challenges, and (4) Diverse experiences with health and social services. The results show further that people with MHD/SUD have challenges with digital tools and/ or do not have the appropriate equipment. Persons with MHD/SUD face greater barriers in accessing the health care system compared to the general population as a control group.
Results of the register study are still preliminary.

Conclusions:
Persons with MHD/SUD face major challenges during the COVID-19 pandemic There is reason to believe that new pandemics will emerge in the future. In this context, it is essential to gain knowledge of how to care for vulnerable groups in society and how to reach them in emergencies.

Key messages:
Continuous maintenance of low-threshold services for persons with MHD/SUD during a pandemic is essential. Improvement of digital skills of service users or alternatives to digital consultations should be considered.

Background:
Regular testing for SARS-CoV-2 is an important strategy for controlling virus outbreaks on university campuses during the COVID-19 pandemic but testing participation can be low. The Residence-Based Testing Participation Pilot (RB-TPP) was a novel 4-week intervention implemented at two student residences on a UK university campus, aiming to increase asymptomatic testing frequency and normalise university life through relaxed social restrictions onsite.

Methods:
Mixed-methods process evaluation determined whether RB-TPP was implemented as planned and identified implementation barriers and facilitators. Data were collected from meeting records, university students (online survey: n = 152; focus groups: n = 30), and staff (interviews, n = 13). Barriers and facilitators to implementation were mapped to the 'Capability, Opportunity, Motivation-Behaviour' (COM-B) behaviour change framework.

Results:
Uptake was high (n = 464 students opted-in; 98% of those living onsite). Implementation was broadly as planned, with adjustments due to national escalation of the COVID-19 Delta variant. Majority engaged in testing (88%); 46% (52% of testers) were fully compliant with pre-determined testing frequency. Most felt positively towards relaxed social distancing (97.9%). Implementation was facilitated by convenience and efficiency of testing and reduced negative impacts of isolation through opportunities for students to socialise. Barriers to implementation were mixed-messages about the rules, ambivalent attitudes, and lack of adherence to COVID-19 protective measures in the minority.

Conclusions:
This is the first process evaluation of the implementation of asymptomatic SARS-CoV-2 testing in university residences. Testing participation increased and student mental wellbeing improved. Rapid adaptions to the changing pandemic context generated complexity and challenge. Findings have global relevance for outbreak prevention and management strategies in higher education settings.

Key messages:
Delivery of asymptomatic SARS-CoV-2 testing and relaxation of social distancing within residences led to high rates of testing participation and benefits for student mental wellbeing. This is the first process evaluation of the implementation of asymptomatic SARS-CoV-2 testing in university residences with global relevance for outbreak prevention in higher education settings.