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S.J. May, C.C. Blackwell, R.P. Brettle, C.J. MacCallum, D.M. Weir; Non-secretion of ABO blood group antigens: a host factor predisposing to recurrent urinary tract infections and renal scarring, FEMS Microbiology Immunology, Volume 1, Issue 6-7, 1 June 1989, Pages 383–388, https://doi.org/10.1111/j.1574-6968.1989.tb02425.x
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Abstract
In a study of 718 women referred for specialist investigation for recurrent urinary tract infections, 250 (34.8%, P<0.01) were non-secretors. The proportion of non-secretors among the women with renal scars (42.6%) was higher than that found for women with no evidence of renal scars (36.6%). Among 29 patients in whom symptoms began in childhood or adolescence, 51.7% were non-secretors. The proportion of non-secretors among individuals with renal scars in this study (42.6%) and that reported in the accompanying paper for Swedish children (40%) suggests that non-secretion might influence the pathogenic sequelae of these infections. Possible host-parasite interactions underlaying the increased proportion of non-secretors among women with recurrent urinary tract infections and those leading to development of renal scars are discussed.
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.© 1989 Federation of European Microbiological Societies
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