Perspective
Analysis of bacterial metagenomes from the Southwestern Gulf of Mexico for pathogens detection
This perspective provides an analysis of the anthropogenic and natural factors that may be influencing the diversity of pathogenic bacteria in the Southwestern Gulf of Mexico, along with a reflection on the urgent need for studies of the entire marine bacterial diversity in this region.
Minireviews
Functions of galectins as ‘self/non-self’-recognition and effector factors
In this minireview, we discuss the structural basis of carbohydrate recognition by galectins, an evolutionary conserved family of ß-galactoside-binding lectins, and their binding and effector properties for endogenous (‘self’) and exogenous (‘non-self’) glycosylated ligands.
The ironclad truth: how in vivo transcriptomics and in vitro mechanistic studies shape our understanding of Neisseria gonorrhoeae gene regulation during mucosal infection
This article reviews how combining transcriptomics on pathogens from naturally infected hosts and other mechanistic studies can improve our understanding the genes involved in bacterial pathogenesis and how they are regulated.
The sweet side of the pathogenic Neisseria: the role of glycan interactions in colonisation and disease
Glycosylation of the surface of meningococci and gonococci, and interactions with glycan structures of the host, are essential for pathogenic Neisseria colonisation and disease.
Research Articles
Role of extracellular polymeric substances in polymicrobial biofilm infections of Staphylococcus epidermidis and Candida albicans modelled in the nematode Caenorhabditis elegans
The study illustrates the effect of EPS in polymicrobial biofilm infections by using a simple but efficient invertebrate model.
Lactobacilli–lactoferrin interplay in Chlamydia trachomatis infection
The interaction between Lactobacillus brevis and lactoferrin seems to play a role in the protection against Chlamydia trachomatis genital infection.
Comparative pathogenomic characterization of a non-invasive serotype M71 strain Streptococcus pyogenes NS53 reveals incongruent phenotypic implications from distinct genotypic markers
The authors discuss the incongruent genotype:phenotype correlation in Streptococcus.
Deletion of mazF increases Staphylococcus aureus biofilm formation in an ica-dependent manner
This manuscript describes that a chromosomally encoded toxin-antitoxin system in Staphylococcus aureus, MazEFsa, regulates the biofilm formation.
Comparison of the inflammatory response of brain microvascular and peripheral endothelial cells following infection with Neisseria meningitidis
Peripheral and brain microvascular endothelial cells differentially release IL-8, IL-6 and MCP-1 upon infection with Neisseria meningitidis.
Effect of cold water-induced stress on immune response, pathology and fertility in mice during Chlamydia muridarum genital infection
Cold water-induced stress increases the intensity of chlamydia infection, changes pathology and reduces fertility in mice.
Spatial clustering of high load ocular Chlamydia trachomatis infection in trachoma: a cross-sectional population-based study
We identified clusters of high load Ct infections suggesting that high load infections may be important in transmission, which may have implications in trachoma elimination strategies and surveillance.
Burden of Chlamydia trachomatis in India: a systematic literature review
The first systematic literature review on Chlamydia trachomatis in India.
Comparative genomics of free-living Gammaproteobacteria: pathogenesis-related genes or interaction-related genes?
Pathogenicity-related genes were found in a non-human-impacted ecosystem, which leads to the idea that these genes are not necessarily involved in pathogenesis, but in interactions within microbial communities.
High iron supply inhibits the synthesis of the genotoxin colibactin by pathogenic Escherichia coli through a non-canonical Fur/RyhB-mediated pathway
Iron inhibits the synthesis of the genotoxin colibactin by pathogenic Escherichia coli in a Fur/RyhB-independent manner.
Dual action of bacteriocin PLNC8 αβ through inhibition of Porphyromonas gingivalis infection and promotion of cell proliferation
The two-peptide bacteriocin PLNC8 αβ lyses the periodontal pathogen Porphyromonas gingivalis, and suppresses P. gingivalis-mediated cytotoxicity and accumulation of inflammatory mediators from gingival fibroblasts.
