Staphylococcus aureus uses a complex regulatory network to adapt to different environments to support its different lifestyles.
Surprisingly, thickness, density and biomass of biofilms formed by non-typeable Haemophilus influenzae were not significantly correlated with resistance properties.
Hfq and three Hfq-dependent small regulatory RNAs—MgrR, RyhB and McaS—coregulate the locus of enterocyte effacement in enteropathogenic Escherichia coli
This manuscript describes identification of the first regulatory small RNAs that control the virulence of enteropathogenic Escherichia coli.
Simkania negevensis, an emerging Chlamydia-related bacterium, efficiently grows in human cells, suggesting a potential implication in human diseases, and harbors growth characteristics that differ from other known Chlamydiales.
Effect of in vivo neutralization of tumor necrosis alpha on the efficacy of antibiotic treatment in systemic Salmonella enterica infections
Effect of in vivo neutralization of tumor necrosis factor alpha on the efficacy of antibiotic treatment in systemic Salmonella enterica infections.
Identification of unique essential proteins from a Mycobacterium tuberculosis F15/LAM4/KZN phage secretome library
The study aimed to identify unique Mtb secreted proteins from the extensively drug resistant Mtb F15/LAM4/KZN phage secretome library. Based on phage DNA sequencing bioinformatics tools and databases, ten proteins essential for in vivo growth and survival of Mtb (Nrp, PssA, MmpL5, SirA, GatB, EspA, TopA, EccCa1, 38 Rv1634 and Rv3103c) were identified.
Cholesterol metabolism is affected during the acute phase of Chlamydia pneumoniae infection in mice which supports the involvement of this common respiratory bacterium in the development of atherosclerosis.
Involvement of matrix metalloproteinases and their inhibitors in endometrial extracellular matrix turnover in Chlamydia trachomatis-infected recurrent spontaneous aborters
Dysregulated MMPs and TIMPs expression promoted endometrial extracellular matrix degradation and affected early pregnancy eventually leading to spontaneous abortion in Chlamydia trachomatis-infected recurrent aborters.
Sequential colonization of periodontal pathogens in induction of periodontal disease and atherosclerosis in LDLRnull mice
Major periodontal bacterial sequential infection in infected LDLR-deficient mice differs significantly from ApoE−/− mice where bacteria were closely associated with increased atherosclerosis.
Indoleamine 2,3-dioxygenase activity is associated with regulatory T cell response in acute Puumala hantavirus infection
The results provide new information on the immunopathology of acute human hantavirus infections, indicating that indoleamine 2,3-dioxygenase mediates clinically significant immune suppression through regulatory T cells.
The proline residue at position 319 of BvgS is essential for BvgAS activation in Bordetella pertussis
A Bordetella pertussis isolate harboring a spontaneous mutation in the bvgS gene causing a proline-to-threonine substitution at position 319 in the BvgS protein does not express Bvg-regulated virulence factors.