Volume 82, 2024

Selective serotonin reuptake inhibitors (SSRIs) were active against Cryptococcus gattii and in combination with amphotericin B (AmB) exhibited a synergistic effect. Selective serotonin reuptake inhibitors (SSRIs) also reduced capsule size and biofilm, suggesting their potential in cryptococcosis treatments.

This review help readers fully understand the current progression of ZIKV vaccine and enhance the awareness of the prevention of ZIKV.

Several biological agents can reactivate the Epstein–Barr virus, with potential consequences for the human host.

The authors discuss a new axis for hepcidin in liver fibrosis.

Unveiling Acute Undifferentiated Febrile Illness: Global Prevalence, Challenges, and One Health Strategies for Emerging Zoonotic Threats in Resource-Limited Settings.

The use of a combination of non-thermal plasma and antibiotics against dangerous pathogens is a potential solution to the antimicrobial resistance crisis.

This review summarized in detail several factors of Candida albicans inducing macrophage pyroptosis, including hypha formation, cell wall remodeling, candidalysin, and so on, to help us better utilize macrophage pyroptosis, controlling candidal infection, and reduce unnecessary immune damage.

Leprosy, a disabling disease, triggers inflammatory reactions affecting patients. Understanding these reactions is crucial for better treatment, but it's not well-known among healthcare workers caring for leprosy patients.

This review summarizes recent developments in mucosal and Chlamydia immunity applicable to Chlamydia vaccine design.

This review will discuss a single branch of the immune system, so-called “cell-autonomous immunity” and how it is counteracted by Chlamydia species.

In this review, we provide contemporary evidence of the most plausible mechanisms associated with the development of PSGN and highlight future avenues for research.

The review focuses on the global distribution, molecular biology, viral life cycle, host range and transmissibility, and antiviral natural products development of JEV.

This article focuses on an update on zoonotic and other veterinary chlamydiae and their genetic manipulation.

Disrupting quorum sensing as a promising alternative to conventional antimicrobials as part of the One Health initiative.

Respiratory pathogen prevalence in the general population differs between young children and (older) adults and nasal proinflammatory cytokine concentrations associate with the presence of (mild) symptoms of respiratory infection.

Protective anti-chlamydial vaccine regimens induce Ag-specific CD4⁺ T cell response that mediates early inhibition of pathogenic CD8⁺ T cell response following challenge and may serve as a predictive biomarker of protection against Chlamydia -induced chronic pathologies.

Bacterial multi-species invasion of human host cells. UPEC in Orange, Enterococcus facials in green.

Chlamydia nanovaccine development and optimization of immunization routes.

This study delves into the genomic features of a novel attenuated Mycobacterium tuberculosis strain, cultivated for a long period, elucidating its immune response at cellular and in vivo levels. These insights advance tuberculosis pathogenesis understanding and vaccine development.

Chlamydia trachomatis-induced autophagy is regulated via the CYTOR/miR-206/MAPK1 axis.

This paper significantly contributes to Chlamydia vaccine research by analyzing the immunogenicity of a novel antigen, MECA, through computational modeling and in vivo validation, offering valuable insights to vaccine development.

Sphingosine directly targets and kills extra- and intracellular bacteria.

Using genetic mutants, it was shown that a novel Coxiella burnetii protein does not influence the ability of the bacterium to replicate inside eukaryotic cells but does impact a key feature of the space within which the bacteria replicate.

Observation of IF staining of MA104 N*V cells 48 h after infection with Chlamydia trachomatis.

The article reveals that optimal protein allocation is key to understanding Neisseria gonorrhoeae’s metabolism, impacting critical enzymes and energy production pathways.

This study reveals that Uropathogenic Escherichia coli causes significant damage to bladder mucosa, affecting cell integrity, barrier function and contractility, highlighting the potential role of serotonin in bladder infections.

A novel bacteriophage was isolated from hospital wastewater; its genome was analyzed, and when tested with antibiotics, it showed effective results against an MDR A. baumannii. This study could help with treatments for infections.

The rDEV–Pmp17G vaccine was alternative to the major outer membrane protein (MOMP) vaccine against waterflow Chlamydia psittaci infection. Moreover, it was a novel approach for combating chlamydia transmission from animals to humans.

Manuscript shows possible sources of cross-reactivity of pre-pandemic sera with SARS-CoV-2 proteins.

We have performed phylogenetic analysis and defined genotypic features of burn-wound-associated Pseudomonas aeruginosa isolated from burn patients during hospitalization. These burn-wound strains revealed polyclonal infection of some patients while other infections consisted of a clonal infection evolving over time.

Deficiency in a receptor leads to a reduced disease of chlamydia in a mouse model.