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Yves Poirier, Douglas Dennis, Karen Klomparens, Christiane Nawrath, Chris Somerville; Perspectives on the production of polyhydroxyalkanoates in plants, FEMS Microbiology Reviews, Volume 9, Issue 2-4, 1 December 1992, Pages 237–246, https://doi.org/10.1111/j.1574-6968.1992.tb05843.x
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Abstract
Poly-β-hydroxybutyrate (PBH) was recently shown to be produced in genetically engineered plants which expressed the genes from Alcaligenes eutrophus responsible for the formation of PHB from acetoacetyl-CoA. The transgenic plants accumulated PHB as granules which were similar in size and appearance to the bacterial PHB granules. These observations suggest that large scale production of PHB and other polyhydroxyalkanoates in genetically altered crop plants may be feasible.
References
[1]
Anderson
A.J.
Dawes
E.A.
1990
) Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates
Microbiol. Rev.
, 54
, 450
–472
.[2]
Byrom
D.
1987
) Polymer synthesis by microorganisms: technology and economics
Trends Biotechnol.
, 5
, 246
–250
.[3]
Martin
J.H.
Leonard
W.H.
Stamp
D.L.
1976
) Potatoes
, In Principles of Field Crop Production
pp 898
–932
Macmillan
, New York
Chapter 36.[4]
Hiatt
A.
Cafferkey
R.
Bowdish
K.
1989
) Production of antibodies in transgenic plants
Nature
, 342
, 76
–78
.[5]
De Zoeten
G.A.
Penswick
J.R.
Horisberger
M.A.
Ahl
P.
Schultze
M.
Hohn
T.
1989
) The expression, localization, and effect of a human interferon in plants
Virology
, 172
, 213
–222
.[6]
Moffat
A.S.
1992
) High-tech plants promise a bumper crop of new products
Science
, 256
, 770
–771
.[7]
Poirier
Y.
Dennis
E.
Klomparens
K.
Somerville
C.
1992
) Polyhydroxybutyrate, a biodegradable thermoplastic, produced in transgenic plants
Science
, 256
, 520
–523
.[8]
Steinbüchel
A.
Schlegel
H.G.
1991
) Physiology and molecular genetics of poly(β-hydroxyalkanoic acid) synthesis in Alcaligenes eutrophus
Mol. Microbiol.
, 5
, 535
–542
.[9]
Benfey
P.N.
Chua
N.-H.
1990
) The cauliflower mosaic virus 35S promoter: combinatorial regulation of transcription in plants
Science
, 250
, 959
–966
.[10]
Janes
B.
Hollar
J.
Dennis
D.
1990
) Molecular characterization of the poly-β-hydroxybutyrate biosynthesis pathway of Alcaligenes eutrophus H16
In Novel Biodegradable Microbial Polymers
Dawes
E.A.
175
–190
Kluwer
, Dordrecht
.[11]
Peoples
O.P.
Sinskey
A.J.
1989
) Poly-β-hydroxybutyrate biosynthesis in Alcaligenes eutrophus H16: characterization of the gene encoding β-ketothiolase and acetoacetyl-CoA reductase
J. Biol. Chem.
, 264
, 15293
–15297
.[12]
Leutwiler
L.S.
Hough-Evans
B.R.
Meyerowitz
E.M.
1984
) The DNA of Arabidopis thaliana
Mol. Gen. Genet.
, 194
, 15
–23
.[13]
Campbell
W.H.
Gowri
G.
1990
) Codon usage in higher plants, green algae, and cyanobacteria
Plant Physiol.
, 92
, 1
–11
.[14]
Peoples
O.P.
Sinskey
A.J.
1989
) Poly-β-hydroxybutyrate (PHB) biosynthesis in Alcaligenes eutrophus: identification and characterization of the PHB polymerase gene (phbC)
J. Biol. Chem.
, 264
, 15298
–15303
.[15]
Tepfer
M.
Taylor
E.P.
1981
) The permeability of plant cell walls as measured by gel filtration chromatography
Science
, 213
, 761
–763
.[16]
Baron-Epel
O.
Gharyal
P.K.
Schindler
M.
1988
) Pectins as mediators of wall porosity in soybean cells
Planta
, 175
, 389
–395
.[17]
Lundgren
D.G.
Pfister
R.M.
Merrick
J.M.
1964
) Structure of poly-β-hydroxybutyric acid granules
J. Gen. Microbiol.
, 34
, 441
–446
.[18]
Boatman
E.S.
1964
) Observation on the fine structure of spheroplasts of Rhodospirillum rubrum
J. Cell Biol.
, 20
, 297
–311
.[19]
Roughan
P.G.
Slack
C.R.
1982
) Cellular organization of glycerolipid metabolism
Annu. Rev. Plant Physiol.
, 33
, 97
–132
.[20]
Scott
C.C.L.
Finnerty
W.R.
1976
) Characterization of intracytoplasmic hydrocarbon inclusions from the hydrocarbon-oxidizing Acinetobacter species H01-N
J. Bacteriol.
, 127
, 481
–489
.[21]
Ostle
A.G.
Holt
J.G.
1982
) Nile Blue A as a fluorescent stain for poly-β-hydroxybutyrate
Appl. Environ. Microbiol.
, 44
, 238
–241
.[22]
Alberts
B.
Bray
D.
Lewis
J.
Raff
M.
Roberts
K.
Watson
J.D.
1983
) The cell nucleus
Molecular Biology of the Cell
, 432
–434
Chapter 8.[23]
Müller-Röber
B.
Sonnewald
U.
Willmitzer
L.
1992
) Inhibition of the ADP-glucose pyrophosphorylase in transgenic potatoes leads to sugar-storing tubers and influences tuber formation and expression of tuber storage protein genes
EMBO J.
, 11
, 1229
–1238
.[24]
Hershey
H.P.
Stoner
T.D.
1991
) Isolation and characterization of cDNA clones for RNA species induced by substituted benzenesulfonamides in corn
Plant Mol. Biol.
, 17
, 679
–690
.[25]
Huisman
G.W.
de Leeuw
O.
Eggink
G.
Witholt
B.
1989
) Synthesis of poly-3-hydroxyalkanoates is a common feature of fluorescent pseudomonads
Appl. Environ. Microbiol.
, 55
, 1949
–1954
.[26]
Doi
Y.
1990
) Microbial Polyesters
VCH
, New York
.[27]
Goodwin
T.W.
Mercer
E.I.
1983
) Respiration
, In Introduction to Plant Biochemistry
pp 162
–226
Pergamon
, Oxford
Chapter 6.[28]
Haywood
G.W.
Anderson
A.J.
Williams
D.R.
Dawes
E.A.
Ewing
D.F.
1991
) Accumulation of a poly(hydroxyalkanoate) copolymer containing primarily 3-hydroxyvalerate from simple carbohydrate substrate by Rhodococcus sp. NCIMB 40126
Int. J. Biol. Macromol.
, 13
, 83
–88
.[29]
Huijbert
G.N.M.
Eggink
G.
de Waard
P.
Huisman
G.W.
Witholt
B.
1992
) Pseudomonas putida KT2442 cultivated on glucose accumulates poly(3-hydroxyalkanoates) consisting of saturated and unsaturated monomers
Appl. Environ. Microbiol.
, 58
, 536
–543
.[30]
Williams
D.H.
Stone
M.J.
Hauck
P.R.
Rahman
S.K.
1989
) Why are secondary metabolites (natural products) biosynthesized?
J. Nat. Prod.
, 52
, 1189
–1208
.© 1992 Federation of European Microbiological Societies
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