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Pseudomonas aeruginosa
Journal Article
Structural analysis of novel drug targets for mitigation of Pseudomonas aeruginosa biofilms
FEMS Microbiology Reviews, Volume 47, Issue 5, September 2023, fuad054, https://doi.org/10.1093/femsre/fuad054
Published: 28 September 2023
...Moumita Ghosh; Shikha Raghav; Puja Ghosh; Swagatam Maity; Kavery Mohela; Deepti Jain biofilms Pseudomonas aeruginosa drug discovery in silico screening quorum sensing c-di-GMP Department of Biotechnology 10.13039/501100001407 BT/PR42200/MED/29/1573/2021 Pseudomonas...
Journal Article
Protein secretion in Pseudomonas aeruginosa
FEMS Microbiology Reviews, Volume 9, Issue 1, September 1992, Pages 73–90, https://doi.org/10.1111/j.1574-6968.1992.tb05824.x
Published: 01 September 1992
... The Gram-negative bacterium Pseudomonas aeruginosa secretes many proteins into the extracellular medium. At least two distinct secretion pathways can be discerned. The majority of the exoproteins are secreted via a two-step mechanism. These proteins are first translocated across the inner membrane...
Journal Article
Pseudomonas aeruginosa antigens as potential vaccines
FEMS Microbiology Reviews, Volume 21, Issue 3, November 1997, Pages 243–277, https://doi.org/10.1111/j.1574-6976.1997.tb00353.x
Published: 01 November 1997
... of European Microbiological Societies. 1997 Abstract Pseudomonas aeruginosa is one of the most important opportunistic bacterial pathogens in humans and animals. This organism is ubiquitous and has high intrinsic resistance to antibiotics due to the low permeability of the outer membrane...
Journal Article
Cell envelope proteases and peptidases of Pseudomonas aeruginosa: multiple roles, multiple mechanisms
FEMS Microbiology Reviews, Volume 44, Issue 6, November 2020, Pages 857–873, https://doi.org/10.1093/femsre/fuaa036
Published: 17 August 2020
...Astra Heywood; Iain L Lamont Graphical Abstract Figure. This review describes the wide diversity of proteases and peptidases in the cell envelope of the opportunistic pathogen Pseudomonas aeruginosa ...
Journal Article
Pseudomonas aeruginosa biofilm exopolysaccharides: assembly, function, and degradation
FEMS Microbiology Reviews, Volume 47, Issue 6, November 2023, fuad060, https://doi.org/10.1093/femsre/fuad060
Published: 26 October 2023
... 10.13039/501100000024 FDN154327 NIH 10.13039/100000002 R01AI077628 R01AI134895 R01AI143916 Cystic Fibrosis Canada 10.13039/501100000082 Hospital for Sick Children 10.13039/501100006126 Pseudomonas aeruginosa is a ubiquitous and versatile bacterium able to survive...
Journal Article
Structure, function and regulation of Pseudomonas aeruginosa porins
FEMS Microbiology Reviews, Volume 41, Issue 5, September 2017, Pages 698–722, https://doi.org/10.1093/femsre/fux020
Published: 13 July 2017
... Figure. Porins of Pseudomonas aeruginosa play numerous important functions and their expression seems to be highly regulated, reflecting their involvement in the bacterial adaptability to evolving environmental conditions. 24 04 2017 15 12 2016 As the most...
Journal Article
Sigma factors in Pseudomonas aeruginosa
FEMS Microbiology Reviews, Volume 32, Issue 1, January 2008, Pages 38–55, https://doi.org/10.1111/j.1574-6976.2007.00092.x
Published: 01 January 2008
... into the infection process. Pseudomonas aeruginosa σ factors extracytoplasmic function Since the Haemophilus influenzae sequence was completed in 1995, the National Center for Biotechnology Information (NCBI) has published 463 complete microbial genomes (archaeal, 34, and bacterial, 429...
Journal Article
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Pseudomonas aeruginosa as a model bacterium in antiphage defense research
FEMS Microbiology Reviews, fuaf014, https://doi.org/10.1093/femsre/fuaf014
Published: 16 April 2025
... approaches and classification of the known antiphage defense systems. A special focus is placed on the model bacterial pathogen, Pseudomonas aeruginosa in antiphage defense research. We explore the complexity and adaptability of these systems, which play crucial roles in genome evolution...
Journal Article
Regulation of virulence and antibiotic resistance by two-component regulatory systems in Pseudomonas aeruginosa
FEMS Microbiology Reviews, Volume 33, Issue 2, March 2009, Pages 279–294, https://doi.org/10.1111/j.1574-6976.2008.00135.x
Published: 01 March 2009
... Microbiological Societies 2008 Abstract The Gram-negative opportunistic pathogen Pseudomonas aeruginosa ubiquitously inhabits soil and water habitats and also causes serious, often antibiotic resistant, infections in immunocompromised patients (e.g. cystic fibrosis). This versatility is mediated...
Journal Article
GSP-dependent protein secretion in Gram-negative bacteria: the Xcp system of Pseudomonas aeruginosa
FEMS Microbiology Reviews, Volume 22, Issue 3, September 1998, Pages 177–198, https://doi.org/10.1111/j.1574-6976.1998.tb00366.x
Published: 01 September 1998
... as the general secretory pathway (GSP) and is widely conserved among Gram-negative bacteria. In their great majority, exoproteins use the main terminal branch (MTB) of the GSP, namely the Xcp machinery in Pseudomonas aeruginosa, to reach the extracellular medium. In this review, we will use the P...
Journal Article
Why? – Successful Pseudomonas aeruginosa clones with a focus on clone C
FEMS Microbiology Reviews, Volume 44, Issue 6, November 2020, Pages 740–762, https://doi.org/10.1093/femsre/fuaa029
Published: 29 September 2020
... of Pseudomonas aeruginosa unraveled the occurence of few predominant clones that can thrive in various habitats with clone C one of the most abundant group of closely related strains that harbor common and strain specific entities which provide unique features such as xenologues of core genome genes...
Journal Article
Pseudomonas aeruginosa: a clinical and genomics update
FEMS Microbiology Reviews, Volume 45, Issue 6, November 2021, fuab026, https://doi.org/10.1093/femsre/fuab026
Published: 10 May 2021
..., which allowed for large-scale production (Durand, Raoult and Dubourg 2019 ). The main current antibiotic classes are displayed in Table 1 . Figure 2. Pseudomonas aeruginosa airways infection process. (A) (1) P. aeruginosa attaches to the epithelial surface with its pili...
Journal Article
The structure–function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment
FEMS Microbiology Reviews, Volume 46, Issue 5, September 2022, fuac018, https://doi.org/10.1093/femsre/fuac018
Published: 26 April 2022
... [email protected] Abstract Pseudomonas aeruginosa is a human pathogen associated with both acute and chronic infections. While intensively studied, the basic mechanisms enabling the long-term survival of P. aeruginosa in the host, despite massive immune system attack and heavy...
Image
Pseudomonas aeruginosa airways infection process. (A) (1) P....
Published: 10 May 2021
Figure 2.
Pseudomonas aeruginosa airways infection process. (A) (1) P. aeruginosa attaches to the epithelial surface with its pili and flagella through the asialoGM1 receptor, found in damaged tissue. (2) Pyocyanin and other substances secreted by P. aeruginosa damage the tissue and allow epithelial
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Chemotaxis gene clusters I, II, and V in Pseudomonas aeruginosa. F...
Published: 26 November 2014
Figure 1.
Chemotaxis gene clusters I, II, and V in Pseudomonas aeruginosa . Figure adapted from Guvener et al . ( 2006 ).
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Concentration–response curve for Pseudomonas aeruginosa to phospha...
Published: 26 November 2014
Figure 8.
Concentration–response curve for Pseudomonas aeruginosa to phosphate. Cells were imaged at 20× magnification at 30-s intervals at the mouth of a capillary containing attractant. Standard deviations for each measurement are shown. Figure reproduced from Kato et al . ( 1992 ), with permission.
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Model of pyocin regulation in Pseudomonas aeruginosa. (a) In nonin...
Published: 01 July 2014
Figure 8
Model of pyocin regulation in Pseudomonas aeruginosa . (a) In noninducing conditions, expression of pyocin genes is repressed indirectly by PtrR. (b) After DNA-damaging treatment (thunderbolt), RecA is activated (glowing and discolored) and activates autocleavage of PrtR. Consequently, PrtR can
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Virulence of Pseudomonas aeruginosa strains in a murine model of a...
Published: 01 January 2011
Figure 3
Virulence of Pseudomonas aeruginosa strains in a murine model of airways infection. C57Bl/6NCrlBR mice were infected with 1–2 × 10 6 CFU per lung of 32 P. aeruginosa different strains embedded in agar beads. Mortality induced by bacteraemia (red) and survival (grey) were evaluated
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a: Adhesion to polystyrene of Pseudomonas aeruginosa PAO1 (A+...
Published: 01 July 1997
Figure 5
a: Adhesion to polystyrene of Pseudomonas aeruginosa PAO1 (A + B + ) (•) and its LPS derivatives AK1401 (A + B − ) (◯), dps89 (A − B + ) (■) and rd7513 (A − B − ) (□). Washed cell suspensions (ca. 5×10 8 cfu ml −1 ) were incubated (37°C) with hydrophobic SM2 Biobeads. At regular intervals, 1 ml
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Western immunoblots of LPS isolated from Pseudomonas aeruginosa PA...
Published: 01 July 1997
Figure 6
Western immunoblots of LPS isolated from Pseudomonas aeruginosa PAO1 populations which have been growing as biofilms for various times on the surface of DEAE beads. LPS was fractionated by SDS-PAGE, transferred to nitrocellulose, and reacted with MAbs specific for A-band (A) or B-band (B) LPS
