cancer virus

... for oncolytic virus therapies against cancer cells where the UPR^ER is frequently upregulated. We conclude with a discussion of the evolutionary impact that viruses, in particular retroviruses, and anti-viral defense has on the UPR^ER. Although viruses trigger robust stress responses...

... are widely used by many viruses, including herpesviruses, for virus attachment, virus endocytosis and cellular activation, which facilitates virus entry into host cells (Stewart and Nemerow 2007 ). It was proposed that EBV may also use integrins as epithelial cell entry receptors because an integrin-binding...

.... You S.-L. Chen C.-J. ( 1992 ) The role of hepatitis B and C viruses in hepatocellular carcinoma in a hepatitis B endemic area: a case/control study Cancer , 69 , 2052 – 2054 . 48...

... into the antiviral or proviral group because of their dual positive and negative antiviral roles. Discrepant conclusions concerning the effect of ZFP on a certain virus were drawn from distinct perspectives. Therefore, we categorize and discuss them separately. A member of ZFPs with uncertain effects on viruses...

..., the pneumonia virus of mice and the avian pneumovirus. The Paramyxoviridae family also includes the subfamily Paramyxovirinae , which includes measles, mumps, Newcastle disease (NDV) and human parainfluenza viruses, and genus Respirovirus, which includes Sendai virus. Vesicular stomatitis (VSV...

.... Tajiri M. Yamaguchi K. Takatsuki K. ( 1987 ) Human T-cell leukemia virus type I infection in hemodialysis patients Cancer , 60 , 1474...

... implicated in cancers and their progression. Bacteriophages are viruses that infect specific bacteria in a lysogenic or lytic manner (Knoll and Mylonakis 2014 ). During lysogenic infection, bacteriophages integrate their genome into that of the bacteria where the virus may remain dormant until specific...

... the paradigm shift towards a genetic component of cancer susceptibility, the viral theory of cancer ‘aspired to explain most or all types of the disease as being induced by viruses’ (Duran-Reynals 1953 ). The viral aetiology of human warts had been established through classic filtration...

...Hao Su; Henley Cheung; Harry Cheuk-Hay Lau; Hongyan Chen; Xiaoting Zhang; Na Qin; Yifei Wang; Matthew Tak Vai Chan; William Ka Kei Wu; Huarong Chen Table 2. The role of m6A regulators in cancer. Regulator Cancer type Role Targets Function Reference METTL3 CRC oncogene SOX2...

... of a polyoma virus mutant defective in binding and activating PI3-K provided evidence of a role of PI3-K/Akt signalling in blocking apoptosis by polyoma viruses [83] . Figure 5 Possible mechanism of immune escape of HCMV-infected cells due to up-regulation of FasL. (A) Non-infected tumor cells expressing...

... carcinoma and the 10% of EBV-associated gastric carcinoma are most likely not a component of the EBV life cycle in healthy virus carriers. KS is the most common AIDS-associated cancer and in contrast to EBV, all of the KSHV-associated malignancies are considerably increased in the HIV-infected population...

... in the three domains of life: Archaea, Bacteria and Eukarya. The physiological and/or evolutionary relationships between EVs and viruses are also examined. extracellular vesicles nanotubes Archaea virus evolution LUCA The release of membrane-bound vesicles is a universally conserved cellular process...

... of a virus that produced a fatal leukemia when inoculated into adult mice. This was a time when the concept of viruses causing cancer was still viewed with extreme skepticism and the presentation of such data by a young woman not long out of graduate school was met with disbelief and derision’ (Diamond 1994...

... ). The Kaposi's sarcoma-associated herpes virus (KSHV, or HHV-8) is an oncovirus responsible for several cancers arising in immunocompromised (mainly AIDS) patients, notably the Kaposi's sarcoma. With this virus, productive infection is not the rule and KSHV rather establishes a latent infection with periodic...

...: Laboratory of Tumor Cell Biology, National Cancer Institute, National Institutes of Health, Bcthesda, MD of one of the virus coat proteins; provided the modi- 20892, LISA. fied coat protein remains compatible with virus as- 0168-6445/95/$29.00 © 1995...

.... , 1994 ; Martínez-Ruiz et al. , 2001 ). Thus, although any ribosome could be potentially inactivated by these proteins, owing to the universal conservativeness of the SRL, they are especially active on transformed or virus-infected cells ( Olson et al. , 1965 ; Fernández...

..., a second group of agents, the dependoviruses, can replicate only in cells which are co-infected with an adeno-, herpes, or vaccinia virus. They thereby interfere with multiplication of their helper as well as with its ability to transform cells and to induce tumors. In the absence of helper viruses...

... of the immunity would function in the difficult environment of the stomach. A vaccine against the human papillomavirus serotype 16 causing cancer of the uterine cervix is likewise approaching clinical trials. Such a vaccine could not have been developed without modern biotechnology since the virus cannot be grown...

...% vs. 0.2%) it can c be sc .~ risk for development o dmilar. Obviously, chronic HCV infection live2r cancer (HCL) is nighigh min Japan but probabl lOt always have a poor long-term outcome. low in Italy as judged from 1these studies. HC'~ [n an(mother recent long...

... nephrotoxicity (Tippin et al. 2016 ). Chimerix, Inc., the company that further developed BCV, demonstrated that it is a broad spectrum antiviral active against five families of double-stranded DNA viruses (reviewed in (Painter et al. 2012 ; Florescu and Keck 2014 )). Studies in cell culture...