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Volume 17, Issue 1
January 2017
ISSN 1567-1356
EISSN 1567-1364
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Editorial

Retrospective

Over 40 years of research on yeast from mitochondrial DNA to mitochondrial diseases.

Tags: yeasts

Minireviews

This article discusses the development of logical modeling of cell cycle regulation in Saccharomyces cerevisiae and perspectives for its integration with cellular networks for multi-scale models.

DNA motor protein-mediated replication fork regression can restart stalled replication but may also generate dangerous outcomes. Positive and negative regulators can influence the outcomes depending on the specific molecular settings.

Quiescence unveils a novel mutational force.

Many ‘buffer genes’ affect rDNA stability and cellular senescence.

Research Articles

Mechanisms of mutant huntingtin toxicity in yeast can differ between strains.

Genome-wide high-throughput screens are powerful tools that enable identification of established and novel genes involved in recombinant protein expression.

Sugar consumption and (off-)flavor production by Brettanomyces bruxellensis is dependent on both the yeast strain and medium composition.

Protamine peptide and its cyclized form exhibit a concentration dependent mode of action.

Sch9p and Gcn4p profoundly impacted wine yeast physiology during grape juice fermentation, and not only affected nitrogen but also carbon metabolism, which affected growth, cell longevity and glycerol production.

Replacement of essential yeast reductase with corresponding gene from apple allows more efficient production of flavonoids by eliminating formation of side products.

Debaryomyces hansenii DEHA2D12848 gene encodes a transcriptional activator for proteasomal genes with unique transactivation domain.

Phylogenetic data on Saccharomyces uvarum strains, isolated for the first time from Patagonian apple chicha suggest that these strains might have been introduced in Patagonia during the domestication of apples by Mapuche communities.

A yeast strain without functional sucrose transport and hydrolysis was constructed and is now ready to be used for metabolic engineering strategies and for fundamental studies into sucrose metabolism.

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