1-20 of 79684
Journal Article
ACCEPTED MANUSCRIPT
Improved sampling of genotypes and species reveals new insights on de novo gene history and regulatory origins Get access
Genetics, iyaf074, https://doi.org/10.1093/genetics/iyaf074
Published: 18 April 2025
Journal Article
Biobanks in GENETICS and G3: tackling the statistical challenges
Genetics, Volume 229, Issue 4, April 2025, iyaf046, https://doi.org/10.1093/genetics/iyaf046
Published: 17 April 2025
Journal Article
ACCEPTED MANUSCRIPT
A multigenerational population-growth assay to capture subtle fitness phenotypes in C. elegans and other nematodes Get access
Genetics, iyaf073, https://doi.org/10.1093/genetics/iyaf073
Published: 16 April 2025
Journal Article
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Testing for differences in polygenic scores in the presence of confounding Get access
Genetics, iyaf071, https://doi.org/10.1093/genetics/iyaf071
Published: 15 April 2025
Journal Article
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Living in poverty is associated with gene expression changes in immune cells Get access
Genetics, iyaf072, https://doi.org/10.1093/genetics/iyaf072
Published: 11 April 2025
Journal Article
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Alternate genetic paths of adaptation to spectinomycin in Escherichia coli Get access
Genetics, iyaf069, https://doi.org/10.1093/genetics/iyaf069
Published: 10 April 2025
Journal Article
Chromatin and epigenetics in aging biology Get access
Genetics, iyaf055, https://doi.org/10.1093/genetics/iyaf055
Published: 09 April 2025
Image
Summary of the chromatin factors shown to regulate lifespan. Many chromatin... Get access
Published: 09 April 2025
Fig. 1.
Summary of the chromatin factors shown to regulate lifespan. Many chromatin-modifying enzymes and chromatin-binding proteins have been shown to regulate longevity in C. elegans. Those demonstrated to extend lifespan when mutated or overexpressed are highlighted. Proteins shown in circles have been
Journal Article
ACCEPTED MANUSCRIPT
Dimensionality Reduction of Genetic Data using Contrastive Learning
Genetics, iyaf068, https://doi.org/10.1093/genetics/iyaf068
Published: 07 April 2025
Journal Article
ACCEPTED MANUSCRIPT
Analysis of rad-51 separation of function allele suggests divergence of the SDSA and dHJ pathways prior to RAD-51 filament disassembly
Genetics, iyaf063, https://doi.org/10.1093/genetics/iyaf063
Published: 07 April 2025
Journal Article
ACCEPTED MANUSCRIPT
Intrinsically disordered arginine-glycine (RG) repeat domains tune sub-nucleolar compartmentalization in C. elegans Get access
Genetics, iyaf067, https://doi.org/10.1093/genetics/iyaf067
Published: 07 April 2025
Journal Article
Estimation of heritabilities and genetic correlations by time slices using predictivity in large genomic models
Genetics, iyaf066, https://doi.org/10.1093/genetics/iyaf066
Published: 05 April 2025
Image
Heritability estimates for a simulated production trait by generation based...
Published: 05 April 2025
Fig. 1.
Heritability estimates for a simulated production trait by generation based on true breeding values (realized), genomic Gibbs sampling (G-Gibbs), and predictivity.
Image
Genetic correlation estimates by generation based on true breeding values (...
Published: 05 April 2025
Fig. 3.
Genetic correlation estimates by generation based on true breeding values (realized), genomic Gibbs sampling (G-Gibbs), predictivity of production phenotype by fitness GEBV (Pred-PF), and predictivity of fitness genotype by production GEBV (Pred-FP).
Image
Heritability estimates for a simulated fitness trait by generation based on...
Published: 05 April 2025
Fig. 2.
Heritability estimates for a simulated fitness trait by generation based on true breeding values (realized), genomic Gibbs sampling (G-Gibbs), and predictivity.
Journal Article
Origin and establishment of the germline in Drosophila melanogaster
Genetics, Volume 229, Issue 4, April 2025, iyae217, https://doi.org/10.1093/genetics/iyae217
Published: 04 April 2025
Image
Oskar structure and functions in germ granule assembly and translational re...
Published: 04 April 2025
Fig. 2.
Oskar structure and functions in germ granule assembly and translational regulation. a) Domain diagram of Oskar protein. Long and short isoforms use two different start codons: M1 and M139, respectively. Individual functional domains and their functions are shown. b) The function of Long Oskar in th
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Establishing germline-soma dichotomy. Three mechanisms contribute to germ c...
Published: 04 April 2025
Fig. 3.
Establishing germline-soma dichotomy. Three mechanisms contribute to germ cell program. Left: GCL degrades somatic signaling pathways. Middle: Nanos blocks translation of soma-promoting RNAs. Right: Pgc inhibits transcription in pole cells. Images adapted from Martinho et al . (2004) and Cinalli
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Long Oskar function in mitochondrial localization. a) The N-terminal region...
Published: 04 April 2025
Fig. 4.
Long Oskar function in mitochondrial localization. a) The N-terminal region that is unique to the Long Oskar isoform represses the function of Short Oskar, for example, forming germ granules. The structural domains of Oskar protein is shown in the schematics. b) Long Oskar concentrates actin and rec
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The maternal-to-zygotic transition in germ cells. Red gradient depicts tran...
Published: 04 April 2025
Fig. 6.
The maternal-to-zygotic transition in germ cells. Red gradient depicts transcriptional repression, while green gradient represents the gradual transition from the maternal RNA pool provided to the oocyte to zygotic transcription in the embryo. Pgc, Ovo, Nanos, Osa, and Su(var)3-3 contribute to trans
