ASSOCIATIONS OF ACCELEROMETER-MEASURED VOLUME AND INTENSITY OF PHYSICAL ACTIVITY (PA) AND SEDENTARY BEHAVIOR WITH CARDIOVASCULAR DISEASE RISK IN OLDER WOMEN

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A.Z. LaCroix ^2,3,1 , E. Rillamas-Sun ³ , C. Di ³ , D. Buchner ⁴ , D.E. Rosenberg ¹ , K. Evenson ⁵ , M.L. Stefanick ⁶ , 1. Group Health Research Institute, Seattle, Washington,2. University of California San Diego, La Jolla, California,3. Fred Hutchinson Cancer Research Center, Seattle, Washington,4. University of Illinois Urbana Champaign, Urbana, Illinois,5. University of North Carolina, Chapel Hill, North Carolina,6. Stanford, Palo Alto, California

Purpose: The purpose of this study was to determine how physical activity and sedentary behavior are related to cardiovascular disease (CVD) risk factors including BMI, CRP, glucose, insulin, total, HDL and LDL-cholesterol levels, triglycerides and blood pressure in older women. Methods: Among 4870 OPACH women ages 63-99, accelerometer data were used to measure total physical activity (average VM counts/15-sec), and minutes spent in low light, high light, and moderate/vigorous PA and sedentary. Fasting blood specimens were collected during home examination and analyzed at the University of Minnesota. Results: Adjusting for weartime, age, BMI, and race/ethnicity almost all correlations were statistically significant and the largest correlations were observed between the physical activity and sedentary variables and BMI, insulin, HDL-cholesterol and triglycerides. Associations for minutes/day spent in high light activity and sedentary time were most strongly associated with BMI. Conclusions: PA and sedentary behavior are associated with CVD risk factors in older women.