Abstract

School-based employee interventions can benefit the health of staff and have the potential to influence the health of school students through role-modelling. However, interventions within schools typically focus on students, with very few studies addressing obesity and related health behaviours among school staff. A systematic review of the peer-reviewed literature published between January 2000 and May 2020 was undertaken to synthesize the evidence on the impact that school-based obesity prevention programmes have on the staff they employ. Search terms were derived from four major topics: (i) school; (ii) staff; (iii) health promotion and (iv) obesity. Terms were adapted for six databases and three independent researchers screened results. Studies were included if they reported on the outcomes of body weight, dietary behaviours and/or physical activity. Of 3483 papers identified in the search, 13 studies met the inclusion criteria. All 13 studies included an intervention that focussed on improving nutrition, physical activity or both. All included studies demonstrated a positive outcome for either dietary intake, weight or body mass index or physical activity outcomes, however not all results were statistically significant. The included studies showed promising, although limited, impacts on employee health outcomes. This review demonstrated a lack of global focus and investment in interventions targeting school staff, particularly in contrast to the large amount of research on school-based health promotion initiatives focussed on students. There is a need for further research to understand effective interventions to promote health and prevent obesity in this large, diverse and influential workforce.

Lay Summary

School-based health promotion interventions that focus on employees can benefit the health of staff and have the potential to also influence the health of school students through role-modelling. Most published intervention studies within schools have typically focussed on students, however, with very few studies addressing obesity and related health behaviours among school staff. This systematic review summarizes the evidence on the impact of school-based obesity prevention programmes on the outcomes of physical activity, weight or dietary practices of school staff. The search identified 13 relevant studies published since 2000. The findings of this review show that school staff focussed health promotion interventions can positively impact obesity-related outcomes. The small number of available studies, however, demonstrates a lack of research focus and investment in interventions targeting school staff and teachers’ health. The majority of included studies used relatively weak study designs and included small numbers of schools and staff members. This is particularly contrasting to the large body of research on school-based health promotion initiatives focussed on students. There is a need for further research to understand effective interventions to promote health and prevent obesity in this large, diverse and influential workforce.

INTRODUCTION

The Global Burden of Disease Study estimated that obesity affected 2 billion people globally in 2015, imposing an economic burden of US $2.0 trillion in health care costs, mortality and permanent disability, slowed economic growth and lost productivity (Tremmel et al., 2017; Swinburn et al., 2019). If current trends continue, it is estimated that more than half of the world’s population will meet the classifications of overweight and obesity by 2030, posing further significant risks to human health (Kelly et al., 2008). High quality evidence is needed to understand ways to address adult overweight and obesity that can deliver sustained population level benefits.

Workplaces are an important setting for health promotion, given that many adults spend a large proportion of their week in employment settings, and that poor health may lead to detrimental impacts not only for employees themselves, but also for productivity and organizational success (Chalupka, 2011). Workplace health promotion interventions have been shown to be effective in relation to obesity prevention in various employment sectors, including health care settings, office-based workplaces and university settings (Anderson et al., 2009; Verweij et al., 2011; Power et al., 2014; Weerasekara et al., 2016; Tam and Yeung, 2018; Proper and van Oostrom, 2019). A recent review of reviews on the effectiveness of workplace health promotion interventions that synthesized evidence from 23 reviews, found strong evidence for favourable impacts on weight-related outcomes and prevention of mental health disorders (Proper and van Oostrom, 2019).

Despite published evidence on the effectiveness of health promotion interventions in various workplaces, little is known about their effectiveness when targeting school staff and the unique school workplace environment that is characterized by high job demands, busy workload and inflexibility of staff time (Katz et al., 2005).

Health promotion interventions focussed on the education sector have become of increasing interest for governments and policy makers given not only the potential for school employees’ own health benefits, but also the potential for school employees to be positive role-models of healthful behaviour for the children they teach and interact with (Hartline-Grafton et al., 2009; Snelling et al., 2013; Herbert et al., 2017). The World Health Organization’s Health Promoting Schools Framework further highlights the opportunities available through schools towards taking a whole of setting approach to obesity prevention (World Health Organisation, 2017). A recent review of the framework demonstrated its effectiveness with regard to some weight-related and behavioural (diet and physical activity) contributors to obesity in children (Langford et al., 2014). However, the majority of studies only targeted school students, with little published evidence available on the effectiveness of obesity-related health promotion interventions for school staff (Katz et al., 2005).

The Australian school-based workforce comprises a diverse group of adults with a broad range of ages and ethnicities across all localities nationally (Department of Education, 2014). The school-based workforce includes the categories of teaching staff (approximately 70% of the Australian school-based workforce), and non-teaching staff comprising specialist support staff, administrative and clerical staff (including teacher aides and assistants), building operations, general maintenance and other staff. In 2019, there were over 288 000 full-time equivalent (FTE) teaching staff and 132 000 FTE non-teaching staff employed in Australian schools, with over 3.9 million enrolled students (Australian Bureau of Statistics, 2019).

A recent Australian study explored potential opportunities for schools to support healthy eating and physical activity amongst staff (Huse et al., 2020) and found that key barriers to school staff eating healthily and being physically active included lack of time and support for these behaviours and lack of necessary physical infrastructure in the workplace (Huse et al., 2020). Recommendations from this study included adopting a whole of school health promotion policy to support teachers to pursue healthier lifestyles and reduce workplace stress (Huse et al., 2020).

Given the potential that school-based interventions have for improving health, evidence synthesis with a specific focus on staff members health and wellbeing is needed in order to inform future interventions, health promotion programmes and research. We therefore sought to:

  1. Synthesize the literature from quantitative studies reporting on the effectiveness of obesity prevention interventions for school staff; and

  2. Identify the common characteristics of successful interventions.

METHODS

Eligibility criteria

Studies were included if (i) they were published in English between 2000 and 2020; (ii) intervention participants were school staff (primary or secondary schools or equivalent), including teaching, administrative and leadership staff; (iii) the study included a health promotion intervention; (iv) the study design included a control group or before and after measures [i.e. randomized controlled trials (RCTs), quasi-experimental and non-randomized designs] and (v) outcome measures included at least one of; a measure of weight [including body mass index (BMI)], dietary behaviours and/or physical activity. Literature reviews, conference abstracts and editorials were excluded. The decision to include studies from the year 2000 onwards was made following initial trials of the search strategy where it was found that the majority of school-based health promotion literature was published after this date.

Search strategy

The search strategy was developed following a preliminary review of workplace and school-based health promotion interventions. The search was initially conducted on 25 March 2019 and updated on the 14 May 2020 to capture any new publications since initial search. The following databases were included in the search: Medline, CINAHL, EMBASE, Health and Society database (Informit), ERIC and Google Scholar; the search strategy was adjusted for each database and limited to original research published in peer-reviewed journals, published in the English language. The search strategy terms used and journal-specific syntax can be found in Supplementary Table 1. Search terms included combinations, truncations and synonyms of the following: (i) ‘School OR Staff*’ OR teacher* OR employee* OR worker* OR workplace, (ii) Intervention* OR program* OR ‘health promotion’ OR prevent* OR strategy* OR initiative*, (iii) Diet* OR nutrition* OR eating OR consumption OR weight OR overweight OR obesity* OR ‘physical* activity’ OR ‘sedentary behaviour’ OR exercise. Additional articles were identified via a manual search of reference lists.

Study selection

Search results were extracted from databases into Endnote X9 (Clarivate Analytics, USA). Results were then loaded into systematic review software Covidence (Covidence systematic review software, Veritas Health Innovation, Melbourne, Australia), and three reviewers independently screened titles and abstracts using a pre-determined eligibility assessment form. Full texts of all articles included after title and abstract screening were also each reviewed by two reviewers. Any discrepancies through the review process were adjudicated by a senior researcher and resolved by consensus discussion.

Data extraction

Data extraction was completed by the lead researcher; with data from a 10% subsample (n = 3) of papers extracted by a second reviewer which were checked for agreement which was achieved. Key study characteristics were identified and extracted into a pre-determined data extraction form to enable identification of prominent and recurrent themes. The following data were extracted: author, year of publication; type of school (i.e. primary/elementary, secondary); country; study design; participants (i.e. teachers, administration staff); intervention strategies; intervention timeframe; outcome measures; results; conclusions. The detailed data extraction results can be found in Supplementary Table 2.

Data synthesis and analysis

The key characteristics of the included studies were summarized from the information collected in the data extraction form. The primary outcomes of interest were statistically significant changes in diet, physical activity or unhealthy weight measures among school staff as a result of the school-based intervention. Where possible, for all study arms, the mean or median of primary outcome measures was recorded at baseline, post-intervention and any additional follow-up(s). Measures of error were standard error or SD and associated p values for change between or within groups at follow-up(s), and over time were recorded if available. The diverse characteristics of included studies precluded a meta-analysis, with variation in study design, outcome measures and intervention strategies.

Quality assessment

Following data extraction, assessment of methodological quality of included studies was undertaken using the Quality Assessment Tool for Before-After (Pre-Post) Studies with No Control Group (National Heart Lung and Blood Institute, 2020). Each study was assigned an overall quality rating; good, fair or poor, based on an evaluation of risk of bias through key concepts raised in the 12 questions of the quality assessment tool.

RESULTS

The searches retrieved 4300 relevant abstracts in total and after the removal of duplicates (n = 817), 3483 studies were screened by title and abstract as summarized in the PRISMA diagram (Figure 1). The full texts of 46 studies were reviewed and 13 papers were identified that met all inclusion criteria (Shi-Chang et al., 2004; Cheung et al., 2008; Chen et al., 2010; Farag et al., 2010; Siegel et al., 2010; Berger-Jenkins et al., 2014; Lemon et al., 2014; Merrill and Sloan, 2014; Wang et al., 2015; Frerichs et al., 2016; Wang et al., 2016; LeCheminant et al., 2017; Kupolati et al., 2019). Reasons for exclusion at the full text stage included no data reported on changes in staff behaviours, not an intervention study design and not a peer-reviewed publication (e.g. conference abstracts). One relevant abstract was identified via reference searching; however the full manuscript was not available in English and was therefore excluded.

PRISMA flow diagram of included studies.
Fig. 1:

PRISMA flow diagram of included studies.

The key characteristics of included studies are summarized in Table 1, and the detail of all extracted data is provided in Supplementary Table 2. Figure 2 provides a graphical summary of the results with a harvest plot of the intervention effect of studies reporting key obesity-related outcomes (anthropometric indices, dietary behaviour, nutrition knowledge, physical activity behaviour and physical activity knowledge). Six studies focussed specifically on increasing nutrition knowledge or behaviours, two on physical activity alone and five described interventions that addressed both physical activity and nutrition. Study designs included cluster-randomized control trials (four studies), quasi-experimental (four studies), and pre- and post-evaluations without a control group (five studies). Six studies included small sample sizes of participants (<50) (Cheung et al., 2008; Farag et al., 2010; Berger-Jenkins et al., 2014; Frerichs et al., 2016; Wang et al., 2016; Kupolati et al., 2019).

Table 1:

Summary of included studies

Author, year of publicationCountryDesignIntervention focusStrategyOutcomes
Berger-Jenkins et al., 2014USAQuasi-experimentalPhysical activity + nutritionSchool-wide marketing campaign, education, and coaching provided to staff↑ nutrition knowledge scores*
↑ diet scores*
↑ physical activity behaviours
Chen et al., 2010TaiwanQuasi-experimentalNutritionHPS Program implementation (whole of school approach) with nutrition focus↑ nutrition knowledge*
Improved dietary intake behaviour
Cheung et al., 2008Hong KongQuasi-experimentalPhysical activityMarketing campaign (SMS, leaflets, posters)↑ steps at work*
Farag et al., 2010USAPre- and post-interventionPhysical activityWorksite wellness intervention (marketing, provision of equipment, encouragement of physical activity in planning periods).↑ self-reported physical activity levels
Frerichs et al., 2016USAPre- and post-interventionNutritionBuilding renovation followed strategies from the Healthy Eating Design Guidelines for School Architecture↓ percentage of teachers with a high-fat diet*
Kupolati et al., 2019South AfricaQuasi-experimentalNutritionTreatment schools implemented a contextual nutrition education programme (NEP)↑ nutrition knowledge scores
LeCheminant et al., 2017USAPre- and post-interventionPhysical activity + nutritionMulti-component worksite wellness programme↑ in days/week exercised*
↑ min/week exercised*
↑ fruit consumption*
↑ vegetable consumption*
Merrill and Sloan, 2014USAPre- and post-interventionPhysical activity + nutritionWellsteps wellness programme (behaviour change campaigns, incentives, biometric screening)↓ BMI
Lemon et al., 2014USACluster randomized controlled trialPhysical activity + nutritionIntervention targeted environment, policy, organizational culture and individual knowledge, attitudes and skills↓ weight
↓ BMI*
Shi-Chang et al., 2004ChinaPre- and post-interventionNutritionSchool-based working groups, nutrition training and resources for staff + school-wide health promotion initiatives↑ nutrition knowledge*
↑ attention to nutrition
Siegel et al., 2010USACluster randomized controlled trialPhysical activity + nutritionSchool tailored own health promotion interventions targeting staff nutrition, physical activity and stress↓ BMI*
Wang et al., 2016ChinaCluster randomized controlled trialNutritionFormation of school nutrition group, training for teachers, posters, resources, peer support activitiesNo change in teachers’ nutrition-related knowledge, behaviour or attitudes
Wang et al., 2015ChinaCluster randomized controlled trialNutritionHPS intervention. Activities incl. formation of school nutrition group, training for teachers, posters, resources, peer support activities↑ nutrition knowledge*
↑ eating behaviour scores
Author, year of publicationCountryDesignIntervention focusStrategyOutcomes
Berger-Jenkins et al., 2014USAQuasi-experimentalPhysical activity + nutritionSchool-wide marketing campaign, education, and coaching provided to staff↑ nutrition knowledge scores*
↑ diet scores*
↑ physical activity behaviours
Chen et al., 2010TaiwanQuasi-experimentalNutritionHPS Program implementation (whole of school approach) with nutrition focus↑ nutrition knowledge*
Improved dietary intake behaviour
Cheung et al., 2008Hong KongQuasi-experimentalPhysical activityMarketing campaign (SMS, leaflets, posters)↑ steps at work*
Farag et al., 2010USAPre- and post-interventionPhysical activityWorksite wellness intervention (marketing, provision of equipment, encouragement of physical activity in planning periods).↑ self-reported physical activity levels
Frerichs et al., 2016USAPre- and post-interventionNutritionBuilding renovation followed strategies from the Healthy Eating Design Guidelines for School Architecture↓ percentage of teachers with a high-fat diet*
Kupolati et al., 2019South AfricaQuasi-experimentalNutritionTreatment schools implemented a contextual nutrition education programme (NEP)↑ nutrition knowledge scores
LeCheminant et al., 2017USAPre- and post-interventionPhysical activity + nutritionMulti-component worksite wellness programme↑ in days/week exercised*
↑ min/week exercised*
↑ fruit consumption*
↑ vegetable consumption*
Merrill and Sloan, 2014USAPre- and post-interventionPhysical activity + nutritionWellsteps wellness programme (behaviour change campaigns, incentives, biometric screening)↓ BMI
Lemon et al., 2014USACluster randomized controlled trialPhysical activity + nutritionIntervention targeted environment, policy, organizational culture and individual knowledge, attitudes and skills↓ weight
↓ BMI*
Shi-Chang et al., 2004ChinaPre- and post-interventionNutritionSchool-based working groups, nutrition training and resources for staff + school-wide health promotion initiatives↑ nutrition knowledge*
↑ attention to nutrition
Siegel et al., 2010USACluster randomized controlled trialPhysical activity + nutritionSchool tailored own health promotion interventions targeting staff nutrition, physical activity and stress↓ BMI*
Wang et al., 2016ChinaCluster randomized controlled trialNutritionFormation of school nutrition group, training for teachers, posters, resources, peer support activitiesNo change in teachers’ nutrition-related knowledge, behaviour or attitudes
Wang et al., 2015ChinaCluster randomized controlled trialNutritionHPS intervention. Activities incl. formation of school nutrition group, training for teachers, posters, resources, peer support activities↑ nutrition knowledge*
↑ eating behaviour scores

Significant change.

Table 1:

Summary of included studies

Author, year of publicationCountryDesignIntervention focusStrategyOutcomes
Berger-Jenkins et al., 2014USAQuasi-experimentalPhysical activity + nutritionSchool-wide marketing campaign, education, and coaching provided to staff↑ nutrition knowledge scores*
↑ diet scores*
↑ physical activity behaviours
Chen et al., 2010TaiwanQuasi-experimentalNutritionHPS Program implementation (whole of school approach) with nutrition focus↑ nutrition knowledge*
Improved dietary intake behaviour
Cheung et al., 2008Hong KongQuasi-experimentalPhysical activityMarketing campaign (SMS, leaflets, posters)↑ steps at work*
Farag et al., 2010USAPre- and post-interventionPhysical activityWorksite wellness intervention (marketing, provision of equipment, encouragement of physical activity in planning periods).↑ self-reported physical activity levels
Frerichs et al., 2016USAPre- and post-interventionNutritionBuilding renovation followed strategies from the Healthy Eating Design Guidelines for School Architecture↓ percentage of teachers with a high-fat diet*
Kupolati et al., 2019South AfricaQuasi-experimentalNutritionTreatment schools implemented a contextual nutrition education programme (NEP)↑ nutrition knowledge scores
LeCheminant et al., 2017USAPre- and post-interventionPhysical activity + nutritionMulti-component worksite wellness programme↑ in days/week exercised*
↑ min/week exercised*
↑ fruit consumption*
↑ vegetable consumption*
Merrill and Sloan, 2014USAPre- and post-interventionPhysical activity + nutritionWellsteps wellness programme (behaviour change campaigns, incentives, biometric screening)↓ BMI
Lemon et al., 2014USACluster randomized controlled trialPhysical activity + nutritionIntervention targeted environment, policy, organizational culture and individual knowledge, attitudes and skills↓ weight
↓ BMI*
Shi-Chang et al., 2004ChinaPre- and post-interventionNutritionSchool-based working groups, nutrition training and resources for staff + school-wide health promotion initiatives↑ nutrition knowledge*
↑ attention to nutrition
Siegel et al., 2010USACluster randomized controlled trialPhysical activity + nutritionSchool tailored own health promotion interventions targeting staff nutrition, physical activity and stress↓ BMI*
Wang et al., 2016ChinaCluster randomized controlled trialNutritionFormation of school nutrition group, training for teachers, posters, resources, peer support activitiesNo change in teachers’ nutrition-related knowledge, behaviour or attitudes
Wang et al., 2015ChinaCluster randomized controlled trialNutritionHPS intervention. Activities incl. formation of school nutrition group, training for teachers, posters, resources, peer support activities↑ nutrition knowledge*
↑ eating behaviour scores
Author, year of publicationCountryDesignIntervention focusStrategyOutcomes
Berger-Jenkins et al., 2014USAQuasi-experimentalPhysical activity + nutritionSchool-wide marketing campaign, education, and coaching provided to staff↑ nutrition knowledge scores*
↑ diet scores*
↑ physical activity behaviours
Chen et al., 2010TaiwanQuasi-experimentalNutritionHPS Program implementation (whole of school approach) with nutrition focus↑ nutrition knowledge*
Improved dietary intake behaviour
Cheung et al., 2008Hong KongQuasi-experimentalPhysical activityMarketing campaign (SMS, leaflets, posters)↑ steps at work*
Farag et al., 2010USAPre- and post-interventionPhysical activityWorksite wellness intervention (marketing, provision of equipment, encouragement of physical activity in planning periods).↑ self-reported physical activity levels
Frerichs et al., 2016USAPre- and post-interventionNutritionBuilding renovation followed strategies from the Healthy Eating Design Guidelines for School Architecture↓ percentage of teachers with a high-fat diet*
Kupolati et al., 2019South AfricaQuasi-experimentalNutritionTreatment schools implemented a contextual nutrition education programme (NEP)↑ nutrition knowledge scores
LeCheminant et al., 2017USAPre- and post-interventionPhysical activity + nutritionMulti-component worksite wellness programme↑ in days/week exercised*
↑ min/week exercised*
↑ fruit consumption*
↑ vegetable consumption*
Merrill and Sloan, 2014USAPre- and post-interventionPhysical activity + nutritionWellsteps wellness programme (behaviour change campaigns, incentives, biometric screening)↓ BMI
Lemon et al., 2014USACluster randomized controlled trialPhysical activity + nutritionIntervention targeted environment, policy, organizational culture and individual knowledge, attitudes and skills↓ weight
↓ BMI*
Shi-Chang et al., 2004ChinaPre- and post-interventionNutritionSchool-based working groups, nutrition training and resources for staff + school-wide health promotion initiatives↑ nutrition knowledge*
↑ attention to nutrition
Siegel et al., 2010USACluster randomized controlled trialPhysical activity + nutritionSchool tailored own health promotion interventions targeting staff nutrition, physical activity and stress↓ BMI*
Wang et al., 2016ChinaCluster randomized controlled trialNutritionFormation of school nutrition group, training for teachers, posters, resources, peer support activitiesNo change in teachers’ nutrition-related knowledge, behaviour or attitudes
Wang et al., 2015ChinaCluster randomized controlled trialNutritionHPS intervention. Activities incl. formation of school nutrition group, training for teachers, posters, resources, peer support activities↑ nutrition knowledge*
↑ eating behaviour scores

Significant change.

Harvest plot of the intervention effect of included studies reporting key obesity-related outcomes. Height depicts quality assessment [tall (third line) = good, medium (second line) = fair, low (first line) = poor]. Shading of bar = intervention focus (dark grey = physical activity and nutrition, light grey = nutrition, pattern = physical activity). Alphabet characters represent the studies. Studies: a (Berger-Jenkins et al., 2014), b (Chen et al., 2010), c (Cheung et al., 2008), d (Farag et al., 2010), e (Frerichs et al., 2016), f (Kupolati et al., 2019), g (LeCheminant et al., 2017), h (Lemon et al., 2014), i (Merrill and Sloan, 2014), j (Shi-Chang et al., 2004), k (Siegel et al., 2010), l (Wang et al., 2016), m (Wang et al., 2015).
Fig. 2:

Harvest plot of the intervention effect of included studies reporting key obesity-related outcomes. Height depicts quality assessment [tall (third line) = good, medium (second line) = fair, low (first line) = poor]. Shading of bar = intervention focus (dark grey = physical activity and nutrition, light grey = nutrition, pattern = physical activity). Alphabet characters represent the studies. Studies: a (Berger-Jenkins et al., 2014), b (Chen et al., 2010), c (Cheung et al., 2008), d (Farag et al., 2010), e (Frerichs et al., 2016), f (Kupolati et al., 2019), g (LeCheminant et al., 2017), h (Lemon et al., 2014), i (Merrill and Sloan, 2014), j (Shi-Chang et al., 2004), k (Siegel et al., 2010), l (Wang et al., 2016), m (Wang et al., 2015).

Studies identified were predominantly in the USA (seven studies) and China (four studies), and there was one study each in South Africa and Taiwan. Four studies were implemented in schools located in rural areas (Farag et al., 2010; Wang et al., 2015; Frerichs et al., 2016; Wang et al., 2016).

Twelve of the 13 studies demonstrated positive impacts on either nutrition knowledge (Shi-Chang et al., 2004; Chen et al., 2010; Berger-Jenkins et al., 2014; Wang et al., 2015; Kupolati et al., 2019), dietary behaviours (Chen et al., 2010; Berger-Jenkins et al., 2014; Frerichs et al., 2016; LeCheminant et al., 2017), BMI (Siegel et al., 2010; Lemon et al., 2014; Merrill and Sloan, 2014) or physical activity behaviours (Cheung et al., 2008; Farag et al., 2010; Berger-Jenkins et al., 2014). One study showed no impact of the intervention on staff knowledge or behaviours (Wang et al., 2016).

Nutrition interventions

Six studies (Shi-Chang et al., 2004; Chen et al., 2010; Wang et al., 2015; Frerichs et al., 2016; Wang et al., 2016; Kupolati et al., 2019) focussed on improving the nutrition knowledge and behaviours of school staff. Chen et al. (Chen et al., 2010) attempted to assess the impact of a government-initiated Health Promoting School (HPS) programme in Taiwan on staff nutrition knowledge and dietary behaviours. The quasi-experimental study included three study arms: HPS aimed at dietary intervention (n = 1), HPS not aimed at dietary intervention (n = 2) and non-health-promoting school (n = 2). Although no significant difference in BMI was found between the three study arms post-intervention, staff at HPS with a dietary intervention had significantly higher nutrition knowledge scores (p ≤ 0.001) than HPS not aimed at dietary intervention and non-health-promoting schools. Staff at HPS with a dietary intervention also reported better nutrient intake behaviours post-intervention such as eating breakfast, consuming five serves of vegetables and fruits and reading food labels (Chen et al., 2010). However, without baseline measurements, and given the relatively small sample of schools involved, it is difficult to preclude pre-existing differences in behaviours.

Frerichs et al. (Frerichs et al., 2016) studied the impact of environmental changes resulting from a school building renovation in the USA, guided by the evidence-based Healthy Eating Design Guidelines for School Architecture, on school staff members’ eating behaviours. The intervention included environmental changes such as the addition of a teaching kitchen, school garden, removal of vending machines and signage promoting healthy eating. The intervention was associated with a significant reduction in the proportion of school staff reporting consuming a high-fat diet [from 73.7 to 57.1% (p = 0.05)], and several staff health and wellness activities were initiated. Key weaknesses of this study included the small sample size and high attrition rate with greater than 50% lost to follow-up.

A pilot study, by Shi-Chang et al. (Shi-Chang et al., 2004), also implemented a multi-level intervention (The China/WHO project), targeting all levels of the school from individual knowledge, to policy and infrastructure. The pre- to post-intervention design included approximately 700 employees in 12 schools (6 intervention and 6 control) and demonstrated an increase in nutrition knowledge from baseline to study end in the intervention schools. An improvement in nutrition behaviours of staff in intervention schools was also reported, with those staff self-reporting they were more likely to pay attention to the nutritional content of their lunch after the programme was implemented [an increase from 24 to 38% (p ≤ 0.01)]. While the proportion of staff reporting the same dropped in control schools. However, the measures of nutrition knowledge and behaviour used in the study were not robust, overall compromising the reliability of evidence of actual behaviour change or health outcomes. In addition, it was unclear if the staff surveyed at baseline and follow-up were in fact the same staff, further compromising the reliability of the evaluation of nutrition-related knowledge and behaviour change.

One small study by Wang et al. (Wang et al., 2016) (n = 40 teachers surveyed) implemented a randomized intervention trial of a holistic school-based programme to improve nutrition knowledge, attitudes and behaviours in China. The study found no significant difference between intervention and control schools in staff members’ nutrition knowledge, attitudes and behaviours post-intervention (Wang et al., 2016). A similar study, also conducted in China in 2015 (n = 60) aimed to improve nutrition knowledge and eating behaviours of students, parents and school staff by randomly assigning schools to either (i) a holistic intervention using the HPS framework, (ii) a partial intervention with a modified Health Education curriculum or (iii) a non-intervention control. School staff members’ nutrition knowledge increased over the course of the study for all three schools, with the largest improvements in nutrition knowledge among school staff in the partial intervention school (Wang et al., 2015). Eating behaviour scores for staff also improved for all schools, with the greatest improvement seen in the school assigned to the HPS intervention. These studies were limited by their small sample size and short intervention duration (6 and 3 months, respectively).

Kupolati et al. (Kupolati et al., 2019) used a quasi-experimental design to evaluate the implementation of a contextual nutrition education programme (comprising a teachers’ manual, picture book, learners’ workbooks and posters) in primary schools in Gauteng Province, South Africa. Pre- and post-testing were used in the small sample (12 teachers in the intervention school, 11 teachers in the comparison school) and showed significant improvement in intervention teachers’ nutrition knowledge post-implementation compared with controls. Improvements were also seen in dietary practices and nutrition attitudes; however these were not significant when compared with controls.

Physical activity interventions

Two studies (Cheung et al., 2008; Farag et al., 2010) evaluated interventions targeting improvements in physical activity behaviours and knowledge. Cheung et al. (Cheung et al., 2008) reported on a 6-week physical activity intervention in Hong Kong that aimed to increase the physical activity levels of school staff during school hours (n = 38 in the intervention group and 14 in the control). The intervention included text message reminders, education in the form of flyers and posters, as well as providing participants with pedometers (Cheung et al., 2008). Following the intervention, the intervention group had a greater increase in steps at work compared with the control group (p < 0.001) (Cheung et al., 2008). The study design did not allow for differentiation between the effectiveness of each element of the intervention, but a post-intervention survey found that pedometers were most commonly cited as motivating teachers in the intervention group to undertake more steps in their work day (Cheung et al., 2008).

Farag et al. (Farag et al., 2010) describe an intervention to promote physical activity among US school staff that included changing school environments to include physical activity equipment and promotion posters, and provision of pedometers and a physical activity handbook to individual staff members. No significant changes were seen pre- and post-intervention in self-reported physical activity levels [expressed in Metabolic Equivalent Task (MET) minutes per week, from 2337 [95% confidence interval (CI): 1521–3152] MET-minutes/week, to 2566 (95% CI: 1822–3309) MET-minutes/week] (Farag et al., 2010).

Interventions targeting both nutrition and physical activity

Five studies included both nutrition and physical activity outcomes (Siegel et al., 2010; Berger-Jenkins et al., 2014; Lemon et al., 2014; Merrill and Sloan, 2014; LeCheminant et al., 2017). Berger-Jenkins et al. (Berger-Jenkins et al., 2014) describe a 2-year school-based intervention study named ‘Choosing Healthy and Active Lifestyles for Kids’ (CHALK) in the USA, which included a school-wide social marketing campaign. The intervention outcomes included changes in nutrition and physical activity knowledge, attitudes and behaviours of students and staff over time, with a control group added in year two of the study (Berger-Jenkins et al., 2014). The intervention group showed significant improvements in staff nutrition knowledge (p ≤ 0.0001) and nutrition behaviour (p ≤ 0.0001) post-intervention. Self-reported physical activity also increased over time, however not to the point of statistical significance (p = 0.06). Post-intervention no significant differences were detected between the intervention and control group of school staff for nutrition and physical activity knowledge, attitude and behaviour in year 2 of the study. The evaluation had low response rates and high levels of attrition; of the 370 intervention group staff surveyed at baseline, only 99 completed follow-up surveys after 2 years, while among the control group the final survey included only 17 staff.

LeCheminant et al. (LeCheminant et al., 2017) reported on a worksite wellness programme that included 1873 US school employees (75% female). The comprehensive outcome assessment included physical activity behaviours, fruit and vegetable consumption, restful sleep, smoking, alcohol consumption, self-rated health, mental health-related outcomes (stress, depression, life-satisfaction and loneliness) and job-related outcomes (job performance, absenteeism, job-related satisfaction). At the end of 2 years, participants reported a significant increase in physical activity with a 4.8% increase in days participating in exercise each week and a 12.8% increase in minutes participating in exercise each week compared with baseline. Dietary behaviour also improved with a 6.7% increase in fruit consumption (serves per day) and 4.1% increase in vegetable consumption (serves per day) (LeCheminant et al., 2017). The study design did not include a control group and researchers did not measure how much (if at all) the employees engaged with the wellness programme over time, making it difficult to attribute the reported behaviour changes to the programme activities.

Two RCTs evaluated the impact of multi-component interventions in the USA. The study by Lemon et al. evaluated the impact of interventions targeting individual knowledge, attitudes skills, along with organizational culture and nutrition and physical activity policies among 782 school employees, across 12 public schools (Lemon et al., 2014). At the end of the 2-year follow-up, there was a drop-out of 26.5% participants in the intervention group and 20.3% from the control group. The intervention group lost significantly more weight on average, relative to the control group (−1.37 kg, p = 0.04, equal to a reduction of 0.48 units in BMI). There were also improvements in nutrition knowledge and skills among staff who participated in the intervention. Another RCT, by Siegel et al. recruited 413 school staff from eight intervention and eight control schools (Siegel et al., 2010). Employees in the intervention schools reduced their BMI by an average of 0.04 kg/m2, compared with the control group who increased their BMI by an average of 0.37 kg/m2, although overall sample sizes were small (Siegel et al., 2010).

Merrill et al. undertook a large evaluation of the effectiveness of a worksite wellness programme in reducing health risk involving 2411 school staff in the USA (Merrill and Sloan, 2014). The intervention comprised nutrition education and physical activity initiatives in the workplace including biometric screening, culture change and behaviour change campaigns. Post-intervention, 46.0% of all participants in this pre- and post-test study design reduced their BMI, along with reductions in blood pressure, blood cholesterol and blood glucose (Merrill and Sloan, 2014).

Quality assessment

Overall, the studies included were assessed to be of moderate to high risk of bias. No quality threshold was applied, and therefore the results of all 13 included studies is reported here. Most studies had small samples sizes and did not include a control group to assess the effectiveness of the interventions (see Supplementary Table 3). Five of the included studies did not clearly describe their inclusion criteria and four studies did not clearly describe the interventions. Out of the total 13 studies, four did not describe an intervention that would have been equally distributed across the study population (e.g. some parts of the intervention may not have reached all school staff, with teachers being more likely to be exposed).

DISCUSSION

The findings of this review demonstrate a lack of research focus and investment in interventions targeting school staff and teachers’ health over the past two decades internationally. Despite widespread acknowledgement of the importance of school staff as an important population for health promotion, there have only been 13 studies published since 2000, and the majority used relatively weak study designs and included small numbers of schools and staff members. In this review, we found that school staff focussed health promotion interventions positively impacted dietary intake, weight or BMI or physical activity outcomes for staff.

The lack of studies in this review is especially striking when compared with school-based obesity prevention interventions for children, of which there have been at least 50 high quality randomized—or cluster randomized—controlled trials published over the same period, largely in the USA, UK and Europe (Liu et al., 2019). A recent systematic review and meta-analysis of the effect of school-based obesity prevention interventions on BMI or BMI-z score of children and found significant reductions in intervention schools compared with controls for both single- and multi-component interventions (Liu et al., 2019). Such school-based studies have the potential to also impact the staff they employ, however the direct impacts remain unknown because interventions and evaluations rarely focus on school staff.

Despite good evidence internationally for workplace health promotion, we found that in the school setting high quality studies evaluating the impacts on staff are lacking. The staff focussed interventions identified in this review showed promise, especially those that aimed to improve both physical activity and diet, however sample sizes were small and research designs lacked robustness, severely limiting the generalizability of results. Almost half of the included papers had an evaluation sample comprising fewer than 50 participants, and despite comprehensive intervention strategies, were under-powered to identify intervention effects. Also, the main positive findings were of knowledge gain, which we know is a very early step in the complex pathway to behaviour change.

Several of the studies that used multi-level interventions showed promise (Shi-Chang et al., 2004; Chen et al., 2010; Farag et al., 2010; Lemon et al., 2014; Merrill and Sloan, 2014; Wang et al., 2015; LeCheminant et al., 2017). Addressing multiple drivers of obesity and ill-health through more comprehensive approaches recognizes the complex nature of behaviour change and preventing obesity; however, far more research would be required to identify and prioritize the most effective strategies and approaches to achieve healthier behaviours and weight status among school staff.

Schools have been identified as a priority target for addressing childhood overweight and obesity (Dehghan et al., 2005). An important consideration for research focussed on school staff health and behaviour, is that staff are also in a position to facilitate improvements in children’s health behaviours, and subsequently overweight and obesity rates. A recent study showed that teachers who are focussed on improvements in their own health tend to create classrooms in which obesity prevention efforts are better supported (Esquivel et al., 2016). For example, a teacher who is actively increasing their physical activity level, along with experiencing positive health effects of the change, will be more likely to encourage physical activity among their students (Esquivel et al., 2016). Joint interventions, with components tailored towards improving both staff and students’ health have the potential to prevent obesity across the lifespan, in both children and adults, and should be priority areas for future research.

It is recognized that the working conditions of the school-based workforce can be stressful, characterized by high job stress-related workers compensation claims, high burnout reflecting high workload requirements and poor work/life balance (Lever et al., 2017; Arvidsson et al., 2019). As outlined in the WHO Healthy Workplaces Model, interventions targeting the school-based workforce should address both the working conditions that affect health behaviours and offering health behaviour change to optimize impacts (World Health Organisation, 2007). This is an important consideration for future research.

Strengths and weaknesses

This is the first systematic review of the literature to synthesize the evidence on interventions targeting the health of school staff internationally. A strength of this study is that we used broad search terms in five databases, across literature from the years 2000 to 2020. Despite this, there was only a small number of highly diverse, and largely poor quality, studies that met the inclusion criteria, and this precluded a meta-analysis. As with all systematic reviews, the evidence synthesis here could be limited by publication bias, where studies with neutral or negative results may not be published thus skewing results.

CONCLUSIONS

This review demonstrates extensive gaps in the evidence base for interventions that seek to improve the health of teachers and school staff, globally. Studies are needed across all contexts and especially in rural or disadvantaged communities. Although the interventions here showed promise in improving diet and physical activity in school staff and associated health risk factors, the health of this large and influential population group needs further focus and research investment.

Supplementary Material

Supplementary material is available at Health Promotion International online.

Supplementary Table 1: Search strategy terms.

Supplementary Table 2: Detailed data extraction.

Supplementary Table 3: Quality assessment of included studies.

Funding

This work was supported by Teachers Health Foundation.

Acknowledgements

We also acknowledge the contribution of the Deakin University librarian.

Protocol and Registration

This systematic review was conducted and reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement guidelines (Moher et al., 2009) and followed the pre-specified methods documented in the review protocol as submitted to the International Prospective Register of Systematic Reviews (PROSPERO ID: CRD42019127773) on 14 March 2019.

Conflict of Interest

There are no conflicts of interest to declare.

REFERENCES

Anderson
,
L. M.
,
Quinn
,
T. A.
,
Glanz
,
K.
,
Ramirez
,
G.
,
Kahwati
,
L. C.
,
Johnson
,
D. B.
 et al. . (
2009
)
The effectiveness of worksite nutrition and physical activity interventions for controlling employee overweight and obesity: a systematic review.
 
American Journal of Preventive Medicine
,
37
,
340
357
.

Arvidsson
,
I.
,
Leo
,
U.
,
Larsson
,
A.
,
Håkansson
,
C.
,
Persson
,
R.
and
Björk
,
J.
(
2019
)
Burnout among school teachers: quantitative and qualitative results from a follow-up study in southern Sweden.
 
BMC Public Health
,
19
,
655
.

Australian Bureau of Statistics.
(
2019
)
4221.0—Schools, Australia, 2019
. https://www.abs.gov.au/statistics/people/education/schools/latest-release (last accessed
13 August 2020
).

Berger-Jenkins
,
E.
,
Rausch
,
J.
,
Okah
,
E.
,
Tsao
,
D.
,
Nieto
,
A.
,
Lyda
,
E.
 et al. . (
2014
)
Evaluation of a coordinated school-based obesity prevention program in a Hispanic community: choosing healthy and active lifestyles for kids/healthy schools healthy families.
 
American Journal of Health Education
,
45
,
261
270
.

Chalupka
,
S.
(
2011
)
Workplace obesity prevention.
 
AAOHN Journal
,
59
,
236
.

Chen
,
Y.-H.
,
Yeh
,
C.-Y.
,
Lai
,
Y.-M.
,
Shyu
,
M.-L.
,
Huang
,
K.-C.
and
Chiou
,
H.-Y.
(
2010
)
Significant effects of implementation of health-promoting schools on schoolteachers’ nutrition knowledge and dietary intake in Taiwan.
 
Public Health Nutrition
,
13
,
579
588
.

Cheung
,
P. P. Y.
,
Chow
,
B. C.
and
Parfitt
,
G.
(
2008
)
Using environmental stimuli in physical activity intervention for school teachers: a pilot study.
 
International Electronic Journal of Health Education
,
11
,
47
56
.

Dehghan
,
M.
,
Akhtar-Danesh
,
N.
and
Merchant
,
A. T.
(
2005
)
Childhood obesity, prevalence and prevention.
 
Nutrition Journal
,
4
,
24
.

Department of Education.
(
2014
)
National Teaching Workforce Dataset—Data Analysis Report
.
Commonwealth of Australia
,
Canberra, ACT
.

Esquivel
,
M. K.
,
Nigg
,
C. R.
,
Fialkowski
,
M. K.
,
Braun
,
K. L.
,
Li
,
F.
and
Novotny
,
R.
(
2016
)
Influence of teachers’ personal health behaviors on operationalizing obesity prevention policy in head start preschools: a project of the Children’s Healthy Living Program (CHL).
 
Journal of Nutrition Education and Behavior
,
48
,
318
325.e311
.

Farag
,
N. H.
,
Moore
,
W. E.
,
Thompson
,
D. M.
,
Kobza
,
C. E.
,
Abbott
,
K.
and
Eichner
,
J. E.
(
2010
)
Evaluation of a community-based participatory physical activity promotion project: effect on cardiovascular disease risk profiles of school employees.
 
BMC Public Health
,
10
,
313
.

Frerichs
,
L.
,
Brittin
,
J.
,
Intolubbe-Chmil
,
L.
,
Trowbridge
,
M.
,
Sorensen
,
D.
and
Huang
,
T. T. K.
(
2016
)
The role of school design in shaping healthy eating-related attitudes, practices, and behaviors among school staff.
 
Journal of School Health
,
86
,
11
22
.

Hartline-Grafton
,
H. L.
,
Rose
,
D.
,
Johnson
,
C. C.
,
Rice
,
J. C.
and
Webber
,
L. S.
(
2009
)
Are school employees role models of healthful eating? Dietary intake results from the ACTION Worksite Wellness Trial.
 
Journal of the American Dietetic Association
,
109
,
1548
1556
.

Herbert
,
P. C.
,
Lohrmann
,
D. K.
and
Hall
,
C.
(
2017
)
Targeting obesity through health promotion programs for school staff.
 
Strategies
,
30
,
28
34
.

Huse
,
O.
,
Palermo
,
C.
,
Evans
,
M.
and
Peeters
,
A.
(
2020
)
Factors influencing healthy eating and physical activity amongst school staff.
 
Health Promotion International
,
35
,
123
131
.

Katz
,
D. L.
,
O’Connell
,
M.
,
Yeh
,
M. C.
,
Nawaz
,
H.
,
Njike
,
V.
,
Anderson
,
L. M.
 et al. . (
2005
)
Public health strategies for preventing and controlling overweight and obesity in school and worksite settings: a report on recommendations of the Task Force on Community Preventive Services.
 
Morbidity and Mortality Weekly Report
,
54
,
1
12
.

Kelly
,
T.
,
Yang
,
W.
,
Chen
,
C. S.
,
Reynolds
,
K.
and
He
,
J.
(
2008
)
Global burden of obesity in 2005 and projections to 2030.
 
International Journal of Obesity
,
32
,
1431
1437
.

Kupolati
,
M. D.
,
MacIntyre
,
U. E.
,
Gericke
,
G. J.
and
Becker
,
P.
(
2019
)
A contextual nutrition education program improves nutrition knowledge and attitudes of South African teachers and learners.
 
Frontiers in Public Health
,
7
,
258
.

Langford
,
R.
,
Bonell
,
C. P.
,
Jones
,
H. E.
,
Pouliou
,
T.
,
Murphy
,
S. M.
,
Waters
,
E.
 et al. . (
2014
)
The WHO Health Promoting School framework for improving the health and well-being of students and their academic achievement.
 
Cochrane Database of Systematic Reviews
. doi:10.1002/14651858.CD008958.pub2

LeCheminant
,
J.
,
Merrill
,
R. M.
and
Masterson
,
T. D.
(
2017
)
Changes in behaviors and outcomes among school-based employees in a wellness program.
 
Health Promotion Practice
,
18
,
895
901
.

Lemon
,
S. C.
,
Wang
,
M. L.
,
Wedick
,
N. M.
,
Estabrook
,
B.
,
Druker
,
S.
,
Schneider
,
K. L.
 et al. . (
2014
)
Weight gain prevention in the school worksite setting: results of a multi-level cluster randomized trial.
 
Preventive Medicine
,
60
,
41
47
.

Lever
,
N.
,
Mathis
,
E.
and
Mayworm
,
A.
(
2017
)
School mental health is not just for students: why teacher and school staff wellness matters.
 
Report on Emotional & Behavioral Disorders in Youth
,
17
,
6
12
.

Liu
,
Z.
,
Xu
,
H.-M.
,
Wen
,
L.-M.
,
Peng
,
Y.-Z.
,
Lin
,
L.-Z.
,
Zhou
,
S.
 et al. . (
2019
)
A systematic review and meta-analysis of the overall effects of school-based obesity prevention interventions and effect differences by intervention components.
 
International Journal of Behavioral Nutrition and Physical Activity
,
16
,
95
.

Merrill
,
R. M.
and
Sloan
,
A.
(
2014
)
Effectiveness of a health promotion program among employees in a western United States school district.
 
Journal of Occupational and Environmental Medicine
,
56
,
639
644
.

Moher
,
D.
,
Liberati
,
A.
,
Tetzlaff
,
J.
and
Altman
,
D. G.
(
2009
)
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.
 
Journal of Clinical Epidemiology
,
62
,
1006
1012
.

National Heart Lung and Blood Institute.
(
2020
)
Quality Assessment Tool for Before-After (Pre-Post) Studies with No Control Group
. https://www.nhlbi.nih.gov/health-topics/study-quality-assessment-tools (last accessed
August 2020
).

Power
,
B. T.
,
Kiezebrink
,
K.
,
Allan
,
J. L.
and
Campbell
,
M. K.
(
2014
)
Effects of workplace-based dietary and/or physical activity interventions for weight management targeting healthcare professionals: a systematic review of randomised controlled trials.
 
BMC Obesity
,
1
,
23
.

Proper
,
K. I.
and
van Oostrom
,
S. H.
(
2019
)
The effectiveness of workplace health promotion interventions on physical and mental health outcomes—a systematic review of reviews.
 
Scandinavian Journal of Work, Environment & Health
,
45
,
546
559
.

Shi-Chang
,
X.
,
Xin-Wei
,
Z.
,
Shui-Yang
,
X.
,
Shu-Ming
,
T.
,
Sen-Hai
,
Y.
,
Aldinger
,
C.
 et al. . (
2004
)
Creating health-promoting schools in China with a focus on nutrition.
 
Health Promotion International
,
19
,
409
418
.

Siegel
,
J. M.
,
Prelip
,
M. L.
,
Erausquin
,
J. T.
and
Kim
,
S. A.
(
2010
)
A worksite obesity intervention: results from a group-randomized trial.
 
American Journal of Public Health
,
100
,
327
333
.

Snelling
,
A. M.
,
Ernst
,
J.
and
Belson
,
S. I.
(
2013
)
Teachers as role models in solving childhood obesity.
 
Journal of Pediatric Biochemistry
,
3
,
55
60
.

Swinburn
,
B. A.
,
Kraak
,
V. I.
,
Allender
,
S.
,
Atkins
,
V. J.
,
Baker
,
P. I.
and
Bogard
,
J. R.
(
2019
)
The global syndemic of obesity, undernutrition, and climate change: the lancet commission report.
 
Lancet
,
393
,
791
846
.

Tam
,
G.
and
Yeung
,
M. P. S.
(
2018
)
A systematic review of the long-term effectiveness of work-based lifestyle interventions to tackle overweight and obesity.
 
Preventive Medicine
,
107
,
54
60
.

Tremmel
,
M.
,
Gerdtham
,
U. G.
,
Nilsson
,
P. M.
and
Saha
,
S.
(
2017
)
Economic burden of obesity: a systematic literature review.
 
International Journal of Environmental Research and Public Health
,
14
,
435
. doi:10.3390/ijerph14040435

Verweij
,
L. M.
,
Coffeng
,
J.
,
van Mechelen
,
W.
and
Proper
,
K. I.
(
2011
)
Meta-analyses of workplace physical activity and dietary behaviour interventions on weight outcomes.
 
Obesity Reviews
,
12
,
406
429
.

Wang
,
D.
,
Stewart
,
D.
, and
Chang
,
C.
(
2016
)
A holistic school-based nutrition program fails to improve teachers’ nutrition-related knowledge, attitudes and behaviour in rural China.
 
Health Education
,
116
,
467
475
.

Wang
,
D.
,
Stewart
,
D.
,
Yuan
,
Y.
and
Chang
,
C.
(
2015
)
Do health-promoting schools improve nutrition in China?
 
Health Promotion International
,
30
,
359
368
.

Weerasekara
,
Y. K.
,
Roberts
,
S. B.
,
Kahn
,
M. A.
,
LaVertu
,
A. E.
,
Hoffman
,
B.
and
Das
,
S. K.
(
2016
)
Effectiveness of workplace weight management interventions: a systematic review.
 
Current Obesity Reports
,
5
,
298
306
.

World Health Organisation.
(
2007
)
Workers’ health: global plan of action
. https://www.who.int/occupational_health/WHO_health_assembly_en_web.pdf?ua=1 (last accessed
20 October 2020
).

World Health Organisation.
(
2017
)
Health Promoting Schools: an effective approach to early action on noncommunicable disease risk factors
. https://apps.who.int/iris/bitstream/handle/10665/255625/WHO-NMH-PND-17.3-eng.pdf (last accessed
20 October 2020
).

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