This is a correction to: Inga Dunsche, Ellen L Raddatz, Haide Ismer, Silke Hedtfeld, Stephanie Tamm, Saskia Moser, Julia Kontsendorn, Burkhard Tümmler, Sabina Janciauskiene, Anna-Maria Dittrich, Frauke Stanke, Analysis of CF patient survival confirms STAT3 as a CF-modifying gene with changing impact over time, Human Molecular Genetics, 2022, ddac221, https://doi.org/10.1093/hmg/ddac221

In the originally published version of this manuscript, Table 1 had two columns incorrectly transposed. The information under “Patients' genotype at STAT3: both STAT3Sat alleles =16 ARU” “No of patients, n (%)”, should be swapped with that under “Patients' genotype at STAT3: both STAT3Sat alleles =12 ARU” “No of patients, n (%)”.

This error has been corrected online.

Table 1

Patient survival by STAT3Sat genotype

Year of birthNo of patientsPatients’ genotype at STAT3: both STAT3Sat alleles ≥16 ARUPatients genotype at STAT3: both STAT3Sat alleles ≤12 ARUPatient is heterozygous at STAT3SatP
No of patients, n (%)Median survivalNo of patients, n (%)Median survivalNo of patients, n (%)Median survival
1959–1994165a15 (8.6%)n.d.66 (37.9%)n.d.84 (48.3%)n.d.n.d.
1959–1976787 (8.8%)30 years26 (32.5%)≈50 years45 (56.3%)35 years0.023
1972–1983759 (11.3%)42 years27 (33.8%)36 years39 (48.8%)35 years0.406
1977–1994757 (8.8%)36 years35 (43.8%)32 years33 (41.3%)37 years0.913
Year of birthNo of patientsPatients’ genotype at STAT3: both STAT3Sat alleles ≥16 ARUPatients genotype at STAT3: both STAT3Sat alleles ≤12 ARUPatient is heterozygous at STAT3SatP
No of patients, n (%)Median survivalNo of patients, n (%)Median survivalNo of patients, n (%)Median survival
1959–1994165a15 (8.6%)n.d.66 (37.9%)n.d.84 (48.3%)n.d.n.d.
1959–1976787 (8.8%)30 years26 (32.5%)≈50 years45 (56.3%)35 years0.023
1972–1983759 (11.3%)42 years27 (33.8%)36 years39 (48.8%)35 years0.406
1977–1994757 (8.8%)36 years35 (43.8%)32 years33 (41.3%)37 years0.913

aOut of 174 p.Phe508del-CFTR homozygotes, the STAT3Sat genotype could not be resolved for eight patients. One patient carried SAT3Sat-14 on both chromosomes and thus could not be classified in either group ‘carries at least one allele STAT3Sat-16 or more ARU’ or ‘both alleles STAT3Sat-12 or less ARU’.

Table 1

Patient survival by STAT3Sat genotype

Year of birthNo of patientsPatients’ genotype at STAT3: both STAT3Sat alleles ≥16 ARUPatients genotype at STAT3: both STAT3Sat alleles ≤12 ARUPatient is heterozygous at STAT3SatP
No of patients, n (%)Median survivalNo of patients, n (%)Median survivalNo of patients, n (%)Median survival
1959–1994165a15 (8.6%)n.d.66 (37.9%)n.d.84 (48.3%)n.d.n.d.
1959–1976787 (8.8%)30 years26 (32.5%)≈50 years45 (56.3%)35 years0.023
1972–1983759 (11.3%)42 years27 (33.8%)36 years39 (48.8%)35 years0.406
1977–1994757 (8.8%)36 years35 (43.8%)32 years33 (41.3%)37 years0.913
Year of birthNo of patientsPatients’ genotype at STAT3: both STAT3Sat alleles ≥16 ARUPatients genotype at STAT3: both STAT3Sat alleles ≤12 ARUPatient is heterozygous at STAT3SatP
No of patients, n (%)Median survivalNo of patients, n (%)Median survivalNo of patients, n (%)Median survival
1959–1994165a15 (8.6%)n.d.66 (37.9%)n.d.84 (48.3%)n.d.n.d.
1959–1976787 (8.8%)30 years26 (32.5%)≈50 years45 (56.3%)35 years0.023
1972–1983759 (11.3%)42 years27 (33.8%)36 years39 (48.8%)35 years0.406
1977–1994757 (8.8%)36 years35 (43.8%)32 years33 (41.3%)37 years0.913

aOut of 174 p.Phe508del-CFTR homozygotes, the STAT3Sat genotype could not be resolved for eight patients. One patient carried SAT3Sat-14 on both chromosomes and thus could not be classified in either group ‘carries at least one allele STAT3Sat-16 or more ARU’ or ‘both alleles STAT3Sat-12 or less ARU’.

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