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Volume 23, Issue 24, 15 December 2014
Articles
TCF7L2 is a master regulator of insulin production and processing
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6419–6431, https://doi.org/10.1093/hmg/ddu359
Phenotypic severity of homozygous GCK mutations causing neonatal or childhood-onset diabetes is primarily mediated through effects on protein stability
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6432–6440, https://doi.org/10.1093/hmg/ddu360
The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6441–6447, https://doi.org/10.1093/hmg/ddu362
Selective demethylation and altered gene expression are associated with ICF syndrome in human-induced pluripotent stem cells and mesenchymal stem cells
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6448–6457, https://doi.org/10.1093/hmg/ddu365
Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6458–6469, https://doi.org/10.1093/hmg/ddu366
Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6470–6480, https://doi.org/10.1093/hmg/ddu367
Heterozygous deletion of the Williams–Beuren syndrome critical interval in mice recapitulates most features of the human disorder
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6481–6494, https://doi.org/10.1093/hmg/ddu368
Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6495–6511, https://doi.org/10.1093/hmg/ddu369
Deficiency of Patched 1-induced Gli1 signal transduction results in astrogenesis in Swedish mutated APP transgenic mice
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6512–6527, https://doi.org/10.1093/hmg/ddu370
Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6528–6541, https://doi.org/10.1093/hmg/ddu371
Epigallocatechin-3-gallate and tetracycline differently affect ataxin-3 fibrillogenesis and reduce toxicity in spinocerebellar ataxia type 3 model
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6542–6552, https://doi.org/10.1093/hmg/ddu373
New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6553–6566, https://doi.org/10.1093/hmg/ddu376
A calcineurin- and NFAT-dependent pathway is involved in α-synuclein-induced degeneration of midbrain dopaminergic neurons
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6567–6574, https://doi.org/10.1093/hmg/ddu377
Polycomb group complexes are recruited to reactivated FMR1 alleles in Fragile X syndrome in response to FMR1 transcription
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6575–6583, https://doi.org/10.1093/hmg/ddu378
ZBTB42 mutation defines a novel lethal congenital contracture syndrome (LCCS6)
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6584–6593, https://doi.org/10.1093/hmg/ddu384
The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6594–6606, https://doi.org/10.1093/hmg/ddu385
ASSOCIATION STUDIES ARTICLES
Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6607–6615, https://doi.org/10.1093/hmg/ddu361
Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6616–6633, https://doi.org/10.1093/hmg/ddu363
Genome-wide association and admixture analysis of glaucoma in the Women's Health Initiative
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6634–6643, https://doi.org/10.1093/hmg/ddu364
SUCLG2 identified as both a determinator of CSF Aβ1–42 levels and an attenuator of cognitive decline in Alzheimer's disease
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6644–6658, https://doi.org/10.1093/hmg/ddu372
Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6659–6667, https://doi.org/10.1093/hmg/ddu374
Genome-wide association study of electrocardiographic parameters identifies a new association for PR interval and confirms previously reported associations
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6668–6676, https://doi.org/10.1093/hmg/ddu375
De novo CNVs in bipolar affective disorder and schizophrenia
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6677–6683, https://doi.org/10.1093/hmg/ddu379
Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Pages 6684–6693, https://doi.org/10.1093/hmg/ddu386
Corrigenda
Competing targets of microRNA-608 affect anxiety and hypertension
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Page 6694, https://doi.org/10.1093/hmg/ddu495
Mice with an isoform-ablating Mecp2 exon 1 mutation recapitulate the neurologic deficits of Rett syndrome
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Page 6695, https://doi.org/10.1093/hmg/ddu496
FRONT-MATTER/BACK-MATTER
Cover Page
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Page NP, https://doi.org/10.1093/hmg/ddu591
Contents Page
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Page NP, https://doi.org/10.1093/hmg/ddu590
Editorial Board
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Page NP, https://doi.org/10.1093/hmg/ddu592
Subscription Page
Hum Mol Genet, Volume 23, Issue 24, 15 December 2014, Page NP, https://doi.org/10.1093/hmg/ddu593
