1-20 of 35942
Journal Article
Recombinant human granulocyte–colony stimulating factor for all recurrent miscarriage patients or for a select group?
Human Reproduction, dez147, https://doi.org/10.1093/humrep/dez147
Published: 10 October 2019
Journal Article
Reproduction, DNA methylation and biological age
Human Reproduction, dez149, https://doi.org/10.1093/humrep/dez149
Published: 10 October 2019
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Epigenetic age acceleration associations with parity using three separate m...
Published: 10 October 2019
Epigenetic age acceleration associations with parity using three separate models . (Top row: treated ordinally. Bottom row: live birth categories, relative to nulliparous women) Model 1 adjusts for weight in teens (relative to peers) and early adulthood alcohol and smoking levels (n = 2356); model 2
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Risk of ovarian cancer in women during 22 years after initiating ART treatm...
in Assisted reproductive technology treatment and risk of ovarian cancer—a nationwide population-based cohort study
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Human Reproduction
Published: 10 October 2019
Risk of ovarian cancer in women during 22 years after initiating ART treatment according to female cause of infertility . HRs with 95% confidence limits. Adjusted for educational level, parity, partnership status, treatment year and age. The DANAC-II Cohort 1994–2015.
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Scatter plots between chronological age and DNAm age estimated using the th...
Published: 10 October 2019
Scatter plots between chronological age and DNAm age estimated using the three epigenetic clocks and distributions of the three age acceleration metrics . The scatter plots (top row) show the Pearson correlations. The distributions of the age acceleration metrics (bottom row) include the mean and SD
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Risk of ovarian cancer in women during 22 years after initiating ART treatm...
in Assisted reproductive technology treatment and risk of ovarian cancer—a nationwide population-based cohort study
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Human Reproduction
Published: 10 October 2019
Risk of ovarian cancer in women during 22 years after initiating ART treatment . HRs with 95% confidence limits. Adjusted for educational level, parity, partnership status, treatment year and age. The DANAC-II Cohort 1994–2015.
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Risk of ovarian cancer in women treated with ART according to cause of infe...
in Assisted reproductive technology treatment and risk of ovarian cancer—a nationwide population-based cohort study
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Human Reproduction
Published: 10 October 2019
Risk of ovarian cancer in women treated with ART according to cause of infertility . HRs with 95% confidence limits. Adjusted for educational level, parity, partnership status, treatment year and age. The DANAC-II Cohort 2001–2015.
Journal Article
Assisted reproductive technology treatment and risk of ovarian cancer—a nationwide population-based cohort study
Human Reproduction, dez165, https://doi.org/10.1093/humrep/dez165
Published: 10 October 2019
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Manhattan plot for the epigenome-wide association of parity . The data acco...
Published: 10 October 2019
Manhattan plot for the epigenome-wide association of parity . The data account for relative teenage weight compared to peers (lighter, about same, heavier) and early adulthood smoking (pack yrs.) and alcohol use (drinks/wk.). There were 17 significant CpG sites, using a Bonferroni-corrected P ≤ 1.
Journal Article
Reply: Recombinant human granulocyte colony stimulating factor for all recurrent miscarriage patients or for a select group
Human Reproduction, dez148, https://doi.org/10.1093/humrep/dez148
Published: 10 October 2019
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Mean antral follicle count (AFC) in the biopsied ovary (red) and the contro...
in Biopsying, fragmentation and autotransplantation of fresh ovarian cortical tissue in infertile women with diminished ovarian reserve
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Human Reproduction
Published: 08 October 2019
Figure 1
Mean antral follicle count (AFC) in the biopsied ovary (red) and the control ovary (blue) during the 10 weeks follow-up after the biopsying and autotransplantation . The joint points represent the mean AFC for each visit. The dotted vertical lines represent the standard error of the mean. The straig
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Genomic profile of oxidized DNA extracted by MoDIP . ( A ) Genomic composit...
in Paternal impacts on development: identification of genomic regions vulnerable to oxidative DNA damage in human spermatozoa
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Human Reproduction
Published: 08 October 2019
Genomic profile of oxidized DNA extracted by MoDIP . ( A ) Genomic composition of oxidized DNA extracted from both H 2 O 2 treated (blue) and untreated control samples (orange). ( B ) A total of 54 832 regions were significantly ( P < 0.05) differentially impacted; 51 458 regions with greater a
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Profile of oxidized sperm DNA regions compared to profile of histone- and p...
in Paternal impacts on development: identification of genomic regions vulnerable to oxidative DNA damage in human spermatozoa
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Human Reproduction
Published: 08 October 2019
Profile of oxidized sperm DNA regions compared to profile of histone- and protamine-bound regions of chromosome 15 . The location of oxidized DNA regions (blue) were compared to regions of DNA bound to protamines (red) and to histones (black) previously described by Hammoud et al. (2009 ). ( A )
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Quantification of extracted sperm DNA from healthy donors and infertile pat...
in Paternal impacts on development: identification of genomic regions vulnerable to oxidative DNA damage in human spermatozoa
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Human Reproduction
Published: 08 October 2019
Quantification of extracted sperm DNA from healthy donors and infertile patients at 10 predicted oxidative vulnerable regions . Individual genomic regions predicted to be vulnerable to oxidative damage were analysed by qPCR amplification and quantified using known concentrations of DNA. DNA extracte
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Variation in anti-Müllerian hormone (AMH) and antral follicle count (AFC) i...
in Biopsying, fragmentation and autotransplantation of fresh ovarian cortical tissue in infertile women with diminished ovarian reserve
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Human Reproduction
Published: 08 October 2019
Figure 2
Variation in anti-Müllerian hormone (AMH) and antral follicle count (AFC) in two subgroups of the patients during the 10-week follow-up after the biopsy and autotransplantation . ( A ) Mean AMH. Seven of the 20 patients were classified as having a rise in AMH serum levels 5–8 weeks after the procedu
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Amplification of DNA from Input Control sperm samples before MoDIP . Indivi...
in Paternal impacts on development: identification of genomic regions vulnerable to oxidative DNA damage in human spermatozoa
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Human Reproduction
Published: 08 October 2019
Amplification of DNA from Input Control sperm samples before MoDIP . Individual genomic regions predicted to be vulnerable to oxidative damage were analysed by qPCR amplification, comparing relative quantities in extracted DNA from H 2 O 2 treated and control samples. Quantification of the relative
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Schematic of experimental design . Isolated spermatozoa were cleaned of leu...
in Paternal impacts on development: identification of genomic regions vulnerable to oxidative DNA damage in human spermatozoa
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Human Reproduction
Published: 08 October 2019
Schematic of experimental design . Isolated spermatozoa were cleaned of leucocytes, and each sample (Sperm Sample) (0) was divided into two portions of equal volume and cell number prior to treatment with either 5 m m hydrogen peroxide (H 2 O 2 treated) (1A) or an equal volume of vehicle (Untreate
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Profile of oxidized regions in chromosome 15 . ( A ) Location on chromosome...
in Paternal impacts on development: identification of genomic regions vulnerable to oxidative DNA damage in human spermatozoa
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Human Reproduction
Published: 08 October 2019
Profile of oxidized regions in chromosome 15 . ( A ) Location on chromosome 15 of significant ( P < 0.05) oxidized regions (blue) differentially expressed between H 2 O 2 -treated and untreated control samples. Oxidized regions were detected across the entire chromosome, except on regions 15p13-
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Amplification of DNA from treated and untreated sperm samples at 10 predict...
in Paternal impacts on development: identification of genomic regions vulnerable to oxidative DNA damage in human spermatozoa
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Human Reproduction
Published: 08 October 2019
Amplification of DNA from treated and untreated sperm samples at 10 predicted oxidative vulnerable regions for donors with low basal levels of oxidation . Individual genomic regions predicted to be vulnerable to oxidative damage were analysed by qPCR amplification comparing relative quantities in ex
Journal Article
Evidence that biopsying, fragmentation and auto-transplantation of ovarian tissue should be abandoned as a treatment of diminished ovarian reserve
Human Reproduction, dez158, https://doi.org/10.1093/humrep/dez158
Published: 08 October 2019
